Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: PEA arrived today

Posted by SLS on July 6, 2021, at 11:14:25

In reply to Re: PEA arrived today, posted by linkadge on July 5, 2021, at 17:22:29

> Just to add. I had some PEA from another supplement called "Brain Boost". It contained 90mg of PEA from AFA blue green algae. Although, AFA contains other trace amines as well. This is why I ordered some pure PEA to see the difference.

That sounds encouraging. You might consider taking it in the background while you continue searching for complementary drugs that work synergistically with PEA. When I first started adding Lamictal, I felt a great antidepressant response. However, it waned after a week or so, but it did not stop working completely. Lithium definitely didn't make me feel worse. Because the purported mechanisms of action of Lamictal are so different from anything else, I thought I would keep taking it in the "background" at 300 mg/day while trying other treatments. When I first added lithium to Parnate and Lamictal about 10 years ago, I experienced a significant improvement after my very first dose of lithium at 150 mg. I continued, and went up to 300 mg/day and remained happy with what that dosage. When I increased lithium to 450 mg/day, my response had been reversed. Lithium at 450 mg/day made my depression worse, and included a sort of apathy and lack of creativity.

This was pure empirical observation. My response to lithium follows a bell-shaped curve. Perhaps not so coincidentally, scientists found that the effect of lithium on glutamate concentrations in the hippocampus also follows a bimodal (biphasic) pattern.

In the past, my greatest degree of response came from a combination of TCA + MAOI. A robust remission was achieved using a combination of Parnate + desipramine. However, in retrospect, I realized that there was residual anhedonia. The response I glean from Nardil + nortripyline is broader, and produces a more "pleasant" state of mind, and the anhedonia all but disappeared (MAO-A)?

I experienced several severe, delusional manias in association with MAOIs. This is the diagnostic qualifier that determines my diagnosis being Bipolar Disorder, even though I never experienced a single manic episode without some sort of biological intervention.

I chose to continue with low-dosage lithium, despite my being dubious that it was necessary for my improvement in depression. However, for over 15 years, scientists have reported a lower risk of contracting Alzheimer's Dementia in people who take very low dosages of lithium.

For me, the choice to continue taking lithium at 300 mg/day was obvious.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:SLS thread:1115807