![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 21 of 21. This is the beginning of the thread.
Posted by stan_the_man70 on February 3, 2016, at 10:36:07
This is just my understanding from various sources.
If you have a better summary or understanding or overview or reference then please post.-------------------------------------------
Vitamins :
A vitamins
(animal Retinoids(retinol, retinal, retinoic acid, retinyl esters),
plant Carotenoids (Carotenes(alpha-carotene, beta-carotene, gamma-carotene, delta-carotene, epsilon carotene, zeta-carotene),
Xanthophylls(astaxanthin, beta-cryptoxanthin, canthaxanthin, fucoxanthin, lutein, neoxanthin, violaxanthin, zeaxanthin)) )B vitamins (B1 B2 B3 B5 B6 B7 B9 B12 choline)
Vitamin C ( L-ascorbic acid )
D vitamins (D1 D2 D3 D4 D5)
E vitamins ( four tocopherols (alpha- (α-), beta- (β-), gamma- (γ-), and delta- (δ-)) and
four tocotrienols (alpha- (α-), beta- (β-), gamma- (γ-), and delta- (δ-)))
K vitamins (K1 K2 (MK-4 MK-7) K3 K4 K5)Minerals - copper, zinc, selenium, iron, manganese
-----------------------------------------------------
Natural Phenols :
Flavonoids
(Flavones, Flavonols, Flavanones, Flavanols and their polymers, Isoflavone phytoestrogens, Stilbenoids, Anthocyanins)Phenolic acids and their esters
(Chicoric acid, Chlorogenic acid, Cinnamic acid, Ellagic acid, Ellagitannins, Gallic acid, Gallotannins, Rosmarinic acid, Salicylic acid)Other nonflavonoid phenolics
(Curcumin, Flavonolignans, Xanthones, Eugenol)
Other organic antioxidants (Capsaicin, Bilirubin, Citric acid, N-Acetylcysteine, Lipoic acid, Uric acid)----------------------------------------------
High ORAC exotic fruits :
goji, noni, mangosteen, acai, camu camu, maqui, aloe vera
SCHISANDRA, ROSEHIPS, BAOBAB, ACEROLA CHERRY, AMLA BERRIES, durian fruit, golden berries, Red Jujube Dates, blueberries, seabuckthorn----------------------------------
Classifications and types and categories:Water-soluble (blood plasma surrounding the cells)
Fat-soluble (cell membrane)
Both water-soluble and fat-soluble (inside of the cells, as the cells contain water)Small-molecule antioxidants: (vitamins C and E, glutathione, lipoic acid, carotenoids, and CoQ10)
Large-protein antioxidants: (albumin)Enzymes and coenzymes: produced by body (SOD, glutathione Peroxidase, glutathione reductase , catalase), (DHEA, Coenzyme Q10, Melatonin)
Co-factors: iron, copper, selenium, magnesium, zinc, Iodide
Vitamins: Vitamin A, Vitamin C, Vitamin E, Vitamin K
Phyto: (Carotenoids, Flavonoids, Allyl sulfides, Polyphenols )
Antioxidant proteins: Alpha Lipoic Acid, Glutathione
Hydrogen
Network Antioxidants: work together (Lipoic Acid, Vitamin E, Vitamin C, Coenzyme Q10, Glutathione)
Network Boosters: helpers may not be antioxidants (The Flavonoids Family, The Carotenoids Family, Selenium)Universal Antioxidant: Alpha Lipoic Acid (both fat and water soluble, recycles all other antioxidants)
Master Antioxidant: Gluthatione (ability to regenerate itself and most antioxidants)-------------------------------------------
Antioxidants by probable uses:Brain:
L-Methionine - neurotransmitters
Ginkgo - blood flow
Green Tea - EGCGAnti-inflammatory:
Curcumin - anti-inflammatory and anti-malignancy
Bioperine - improves efficacy
Chaparral - anti cancerCellular: Neutralize superoxide radical and peroxide radicals - mitochondrial energy
Superoxide Dismutase - neutralizes reactive oxygen - superoxide radical - hydroxyl radical
Catalase - neutralize peroxide radicals
Selenium - synergistic with glutathione and catalase
N-Acetyl-Cysteine - raise glutathione
R. Lipoic Acid - mitochondria energy - glutathione boost
Biotin - along with lipoic avid
PQQ - mitochondrial survivalEyes:
Vitamin A
Lutein - combines with vitamin C
Lycopene - zinc antagonist
Bilberry - anthocyanosides - bioflavonoids
Zeaxanthin - xanthophylls
Astaxanthin - Krill
Fucoidan - from seaweedBioflavonoid:
Hesperidin -
Rutin - helps vitamin C
Quercetin - cell wallsOPCs:
Pterostilbene - phytoalexins - mitochondrial function - cardiovascular health - anti-aging and cognitive function
OPCs - oligomeric proanthocyanidins - grape seed extract
Pycnogenol - oxidative stress - bark of the French maritime pine
Resveratrol - grape skin------------------------------------------------------
Posted by stan_the_man70 on February 3, 2016, at 10:37:45
In reply to Antioxidants, posted by stan_the_man70 on February 3, 2016, at 10:36:07
-----------------quote reference
http://www.herbslist.net/herbs-listed-health-condition/
-----------------end quotePosted earlier.
-----------------Anxiety
Ashwagandha
Chamomile
Kava
Lemon Balm
Milk Thistle
Oat Straw
Passionflower
Rhodiola Rosea
Scullcap
St. Johns Wort
Valerian
-------------------Depression
Bacopa
Bee Pollen
Black Cohosh
Eucalyptus
Evening Primrose Oil
Fish Oil
Flaxseed Oil
Ginseng
Gynostemma
Holy Basil
Kava
Lycium Fruit
Maca Root
Rhodiola Rosea
Schizandra
Shilajit
Skullcap
St. Johns Wort
Turmeric
----------------------------------Dementia
Ginkgo
Lemon balm
Sage
Salvia
---------------------------------------Fatigue
Astragalus
Bee Pollen
Black Cohosh
Cordyceps
Ginger
Ginkgo Biloba
Ginseng (Korean, American & Siberian)
Gotu Kola
Gynostemma
Kelp
Licorice Root
Maca
Passionflower
Rhodiola Rosea
Schizandra
Shiitake
Shilajit
Suma Root
-------------------------------Insomnia
Ashwagandha
Chamomile
Hops
Kava
Lavender
Lemon Balm
Passionflower
Scullcap
St. Johns Wort
Valerian
----------------------------------Memory Improvement
Bacopa
Ginkgo
Ginseng (American)
Gotu Kola
Green Tea
Lemon Balm
Sage
Turmeric
-----------------------------------Stress
Ashwagandha
Astragalus
Catnip
Chamomile
Codonopsis
Cordyceps
Dill
Ginko Biloba
Ginseng (Korean, American & Siberian)
Hops
Kava
Lavender
Lemon Balm
Licorice
Lycium
Motherwort
Passionflower
Red Clover
Reishi
Rhodiola Rosea
Rosemary
Sage
Schisandra
Scullcap
St. Johns Wort
Tarragon
Valerian
Vervain
Wood Betony
-------------------------
Posted by stan_the_man70 on February 3, 2016, at 10:45:22
In reply to Herbs By Usage, posted by stan_the_man70 on February 3, 2016, at 10:37:45
-----------------------------------------brain supplements-----------------------
Posted earlier----------------drugs
Adrafinil
Modafinil
Armodafinil
Adderall
Ritalin
Cylert
----------------Ampakines
Sunifiram
Unifiram
Ampalex
-----------------------
----------------choline
Phosphatidylserine - also cell membranes
Carnitine/Acetyl l-carnitine
Choline
Choline Bitartrate + Citrate
Alpha GPC
Citicoline
Centrophenoxine / DMAE
Phosphatidylcholine
Lecithin
Pyritinol - also dopamine
----------------Acetylcholinesterase Inhibitors
Huperzine A
Huperzia Serrata
Galantamine
----------------GABA
GABA
Phenibut
Picamilon
Taurine
Ashwagandha
Kava Kava
Lemon Balm
----------------glutamate
l-theanine
creatine
Agmatime Sulfate
L-Glutamine - also gaba
----------------seratonin
Tryptophan
5-HTP
Griffonia Seed Extract
St Johns Wort
----------------dopamine
Sulbutiamine
DL-Phenylalanine - also dopamine, norepinephrine, epinephrine, and melatonin
Tyrosine
Phenylethylamine
L-Dopa
Mucuna Pruriens
Hordenine - natural derivative of barley grass
----------------testosterone
Sarcosine
DHEA
L-Dopa
----------------cAMP cyclic adenosine monophosphate
Artichoke Extract
Forskolin
------------------------------------
----------------blood flow
Vinpocetine
Vincamine
Propionyl L-Carnitine
Kratom - stimulating, opioid receptor agonists
----------------mitochondrial energy
Alpha Lipoic Acid - damaged neurons
creatine
B vitamins
Co-Enzyme Q10
Rhodiola Rosea
Yerba Mate
Propionyl L-Carnitine
----------------fuel
coconut oil/MCT/ketones
----------------------------------
----------------hormones
iodine
DHEA
Vasopressin
Desmopressin
Melatonin
Pregnenolone
----------------MAO
Rasagiline
Deprenyl
Hordenine
Piperine/pepper vine
Rhodiola Rosea
Yohimbine HCL
----------------methylation
SAMe
------------------------------------
----------------cell walls
fatty acids
omega-3 fish oil
Krill Oil
Phosphatidylserine
----------------neurotransmitters
amino acids
vitamin B
minerals
Magnesium
----------------NGF BNDF
Idebenone
Lions Mane
Selank
----------------cell growth
Cats Claw
Oat Straw - also known as green oat grass
--------------------------------
----------------antioxidant
Alpha-Lipoic Acid
Carnosine
vitamin K2
vitamin D
CoQ10
Idebenone
Grape Seed Extract
Ginseng
Resveratrol
Cat's claw
----------------inflammation
Pterostilbene
Citicoline
Carnosine
Krill/Omega 3/Fish Oil
SAMe
Forskolin
Cat's Claw
----------------immunity
Lysine
Iodine
SAMe
Yerba Mate
DHEA
Green Tea
Cat's claw
-------------------------------------------
----------------nerve transmissions
Bacopa Monnieri
Tyrosine
----------------longevity
Phenylethylamine
Deprenyl
Carnosine
SAMe
Grape Seed Extract
Resveratrol
Cerebrolysin
----------------age-related degenerative protection
Noopept
Choline
Huperzia Serrata
L-Dopa
Stablon
Carnosine
Omega 3
Uridine
Ginseng
Lions Mane
Pterostilbene
----------------neurogenesis
Uridine - also choline
Lions Mane
Marijuana
Cerebrolysin
-------------------------------------
----------------Stimulants
Geranamine
Ephedrine
Nicotine
Octopamine
Yohimbine HCL
Ginseng
----------------Xanthines
Caffeine - blocks adenosine
Green Tea
----------------herbal
Gotu Kola
--------------------------
Posted by stan_the_man70 on February 3, 2016, at 10:52:23
In reply to Brain Supplements, posted by stan_the_man70 on February 3, 2016, at 10:45:22
hey b2chica how are you
how is life - how is sleep - how is weight - how is troubles
exercise - diet - work - social - all going fine if i may askanyway just wanted to let you know a few things that worked for me
coconut oil
avocado oil
butter/butyric oil
grapes seed oil
pumpkin/flax seeds oil
fish/krill oil
rice bran oil
olive oil
algae/algal oil
palm oil
garlic/clove/peanut oil?What I realized is that I cannot eat the same thing every day - because the body adapts - so have to vary it for the week.
Also I found that the oils are not as effective as eating the raw product - because I chew it slowly and maybe it digests betterSo, its in rotations
coconut flakes (dessicated or raw?)
raw avocado slices (guacamole?)
healthy salted butter (with honey, black pepper, turmeric ?)
raw grapes with seeds and skin (juice it with pineapple and melon?)
raw pumpkin/walnut/almond/sesame seeds (raw nut and seed combo pack?)
oily fish and shrimp (steamed or fried?)
soaked black rice (sprouted?)
raw olives (extra virgin olive oil or salad?)
raw seaweed (chlorella spirulina kelp dulce etc ?)not sure about other things such as organ meats, other types of seeds, blueberries - there are so many brain foods the list goes on.
I found the above useful, maybe because its oily.
(have to make sure that the above are digested well.
not sure if any of this would work for you - since you are probably taking a lot of prescriptions.)
thanks, take care.
Posted by SLS on February 3, 2016, at 15:22:35
In reply to Brain Supplements, posted by stan_the_man70 on February 3, 2016, at 10:45:22
I tried taking resveratrol 250 mg/day in an effort to treat bipolar depression. I was hoping that its ability to inhibit PDE4 (phosphodiesterase 4) would go to increase BDNF (brain-derived neurotrophic factor). I was disappointed to see that it made my depression significantly worse within 48 hours.
Maybe I took too much?
- Scott
Posted by stan_the_man70 on February 4, 2016, at 1:12:28
In reply to Re: Brain Supplements - resveratrol » stan_the_man70, posted by SLS on February 3, 2016, at 15:22:35
will try to look at that !
> I tried taking resveratrol 250 mg/day in an effort to treat bipolar depression. I was hoping that its ability to inhibit PDE4 (phosphodiesterase 4) would go to increase BDNF (brain-derived neurotrophic factor). I was disappointed to see that it made my depression significantly worse within 48 hours.
>
> Maybe I took too much?
>
>
>
>
> - Scott
Posted by stan_the_man70 on February 4, 2016, at 1:21:45
In reply to resveratrol » SLS, posted by stan_the_man70 on February 4, 2016, at 1:12:28
Astaxanthin chocolate... for health !!
(maybe even Lutein and Lycopene)Carmit Candy - Dark Chocolate Coins
Esthechoc - from University of Cambridge
Instant bliss beauty - bar/mini/drink - Health by Chocolate
(Disclaimer: just posting it because I found it interesting - I believe these are new products - no commercial endorsements)
Posted by stan_the_man70 on February 4, 2016, at 6:03:49
In reply to Re: Brain Supplements - resveratrol » stan_the_man70, posted by SLS on February 3, 2016, at 15:22:35
Scott - tried to look up info on the subject but there does not seem to be a lot of info on the internet - could not find any research. My thoughts were:
Resveratrol supposedly works as anti-oxidant, anti-inflammatory, anti aging. (SIRT1 gene)
Depression could be caused by inflammation, hormonal changes, neurotransmitters, etc.
Resveratrol could interact with the other medications/minerals/nutrients that you are already taking.
-------------------------
Basically the vitamins can spike up the level of certain hormones/neurotransmitters and then when the effects cease there is depletion which may cause depression. Or it could be causing an imbalance in the delicate state of chemical balance that exists with the medications. Who knows.
This is an interesting thread - pertinent.
http://www.steadyhealth.com/topics/vitamins-depressionAnother long thread on nutrition.
http://nutritionfacts.org/video/antioxidants-and-depression/----------------------
Alternatively, would it be possible to try to juice grapes with seeds, try a different brand of resveratrol, try different quantities, try at different times of the day - because the combinations of things does seem to matter.
---------------------------------------------------------
> I tried taking resveratrol 250 mg/day in an effort to treat bipolar depression. I was hoping that its ability to inhibit PDE4 (phosphodiesterase 4) would go to increase BDNF (brain-derived neurotrophic factor). I was disappointed to see that it made my depression significantly worse within 48 hours.
>
> Maybe I took too much?
>
>
>
>
> - Scott
Posted by SLS on February 4, 2016, at 7:12:36
In reply to Resveratrol » SLS, posted by stan_the_man70 on February 4, 2016, at 6:03:49
Posted by stan_the_man70 on February 4, 2016, at 12:10:20
In reply to resveratrol » SLS, posted by stan_the_man70 on February 4, 2016, at 1:12:28
Did not know this about Resveratrol....------------------quote reference
http://nootriment.com/resveratrol-side-effects/
------------------end quoteResveratrol Side Effects and Possible Health Dangers
Posted by Nootriment Editorial StaffResveratrol Contraindications
There are some people who shouldnt take this supplement. Resveratrol thins the blood and keeps blood pressure in check. It might slow blood clotting, and if it is taken along with similar acting medications it might increase the chances of bruising and bleeding. Below is a list of conditions, herbal remedies and medicines that interact with Resveratrol supplements to cause side effects:resveratrol adverse effects
If taking any of these medications that slow blood clotting, dont take this supplement. These medicines include: Aspirin, Clopidogrel (Plavix), Diclofenac (Voltaren, Cataflam), Ibuprofen (Advil, Motrin), Naproxen (Anaprox, Naprosyn), Dalteparin (Fragmin), Enoxaparin (Lovenox), Heparin and Warfarin (Coumadin).
If taking medications that change in the liver, such as Mevacor, Nizoral, Sporanox, Allegra and Halcion avoid this supplement.
Resveratrol may inhibit cytochrome 3A4, (enzyme in the body, mainly found in the liver and in the intestine) which may cause interactions with HMG-CoA reductase inhibitors, calcium channel agonists and anti-arrhthmic agents.
HIV protease inhibitors and immunosuppressants.
Antihistamines.
Erectile dysfunction medications.
Herbal supplements St. Johns Wort, garlic and ginkgo biloba.
Avoid if allergic to grapes, wine, or any of the ingredients used in the supplement.
If being treated for cancer, or any condition made worse by estrogen, such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids.
Taking MAOI (Monoamine-oxidase inhibitor) anti-depressants. These include: Isocarboxazid (Marplan), Nialamide (Niamid), Phenelzine (Nardil, Nardelzine), Hydracarbazine, Non-Hydrazines: Tranylcypromine (Parnate, Jatrosom), Moclobemide (Aurorix, Manerix), Pirlindole (Pirazidol) (Russia), Toloxatone, (Humoryl) (France), Rasagiline (Azilect), Selegiline (Deprenyl, Eldepryl, Emsam) and Linezolid an antibiotic drug with weak MAO inhibiting activity.
Antiviral or antifungal medication.
Anti-angiogenesis (anti-tumor) effect may not allow tendons and muscles a chance to heal because it suppresses the growth of blood vessels. It is suggested to discontinue supplement for three days to allow healing.
Resveratrol should be stopped at least 2 weeks before surgery.----------------------------
PROS
- Shown to Improve Insulin Sensitivity and Decrease Blood Glucose
- Increases Blood Flow (Including Cerebral Blood Flow)
- Prevents and Decreases Oxidative Damage
- Exhibits a Neuroprotective Effect with Melatonin
- Minpr Improvements in Cholesterol Levels
CONS
- Lower Absoprtion Compared to Pterostilbene
- Some Studies on the Benefits have been Retracted
- May Prevent Benefits of Oxidation Following Intense Exercise
- May Reduce Gains in Athletic Performance and Strength
- No Significant Effects on Fatigue or Cognition-----------------------------------
Other Resveratrol Side Effects
Some people who take the supplement have experienced insomnia, pain in joints, in the hands, legs and hip-joint as well as Achilles tendinitis. It is thought resveratrol increases the NAD+ to NADH ratio. If there is an insufficient niacin or niacinamide as a precursor to manufacture NAD+, tendon pain may be the result. This can be countered by taking niacinamide or a Vitamin B complex. The suggested dose is 250 mg three hours after taking resverarol. With this time interval it wont block resveratrols effects on the sirtuin genes (linked to longevity), but it still provides a source for NAD+.Others have experienced Resveratrol side effects including diarrhea, stomach pain and loss of appetite and nausea. Other symptoms have included dark-colored urine, flu like symptoms, thinning of blood and outbursts of acne. It is thought to be safe during Pregnancy and breast-feeding if taken from food and supplements sources, but not from consuming alcohol. Knowing Resveratrol side effects can prevent any known risks to taking the supplement. Always discontinue a supplement if you do experience any unwanted symptoms to be safe.
Posted by SLS on February 4, 2016, at 13:50:43
In reply to Resveratrol, posted by stan_the_man70 on February 4, 2016, at 12:10:20
Thanks again, S_T_M.
I wish I knew 1/100th about herbs and supplements as you do.
Resveratrol is a very interesting substance. I like what it does neurobiologically. However, I had no idea that it carried such liability for side effects and drug interactions.
- Scott
Posted by SLS on February 4, 2016, at 13:57:49
In reply to Resveratrol, posted by stan_the_man70 on February 4, 2016, at 12:10:20
What herbs or supplements are known to prevent or treat cancer?
Specifically, someone I know has a precancerous cyst on her pancreatic duct (mucinous cystic neoplasm). I am hoping to find something that will slow-down or prevent its conversion to a malignant tumor.
Thanks.
- Scott
Posted by Lamdage22 on February 5, 2016, at 15:48:16
In reply to A quick question... » stan_the_man70, posted by SLS on February 4, 2016, at 13:57:49
Cannabis FTW.
THC, CBD and other cannabinoids destroy cancer cells.
I would recommend vaping. Smoking is not good for cancer.
http://naturalsociety.com/marijuana-kills-cancer-cells-admits-the-u-s-national-cancer-institute/
a good vaping machine:
Posted by Lamdage22 on February 5, 2016, at 15:50:15
In reply to Re: A quick question..., posted by Lamdage22 on February 5, 2016, at 15:48:16
yes there are cheaper ones and mobile ones.
Posted by Christ_empowered on February 6, 2016, at 16:40:20
In reply to Re: A quick question..., posted by Lamdage22 on February 5, 2016, at 15:50:15
The Orthomolecular people claim that more extensive OM protocols (beyond b-100 complex, vitamin C, niacin or niacinamide combinations) can help w/ cancer, whether you opt to do conventional treatments w/ the OM or not.
Common add-ons in OM for cancer: zinc, selenium, natural form vitamin E, beta carotene and other carotenoids, additional b's (folic acid, b6, etc.).
Clearly, I'm a fan of OM, lol. Seriously, though; some OM concepts are being validated, like high dose niacinamide for cancer prevention (skin cancer, I think) and vitamin C injections for cancer patients.
Posted by Lamdage22 on February 9, 2016, at 13:40:45
In reply to Re: A quick question..., posted by Lamdage22 on February 5, 2016, at 15:48:16
Well you cant drive a car.
IDK if i would trust just the Cannabis for this.
Its not serious enough for Chemo??
What do the Drs say?
Posted by B2chica on February 15, 2016, at 17:40:02
In reply to Hey B2chica, posted by stan_the_man70 on February 3, 2016, at 10:52:23
funny, i havent been here forever, until today.
i am not doing well but i'll post more on that below.
i do however greatly apprecaite the folowing suggestions..life- chaotic stability wise
sleep varies from insomnia to hypersomnia
weight-still going up.
excercise- i got on the treadmill last week, then meds and lethargy kicked in and its all i can do to go from my rocking chair to my bed...
diet-too much efffort to care. not eating much during day (no appitite) until about 10 at night than munch on whatever i find in the house
...anyway.
its kinda nice to get a call-out. i really dont know too many people that care these days. ...or understand.
thnx
b2
> hey b2chica how are you
> how is life - how is sleep - how is weight - how is troubles
> exercise - diet - work - social - all going fine if i may ask
>
> So, its in rotations
> coconut flakes (dessicated or raw?)
> raw avocado slices (guacamole?)
> healthy salted butter (with honey, black pepper, turmeric ?)
> raw grapes with seeds and skin (juice it with pineapple and melon?)
> raw pumpkin/walnut/almond/sesame seeds (raw nut and seed combo pack?)
> oily fish and shrimp (steamed or fried?)
> soaked black rice (sprouted?)
> raw olives (extra virgin olive oil or salad?)
> raw seaweed (chlorella spirulina kelp dulce etc ?)
>
> thanks, take care.
Posted by stan_the_man70 on February 17, 2016, at 18:01:50
In reply to A quick question... » stan_the_man70, posted by SLS on February 4, 2016, at 13:57:49
------------------------quote reference
http://well.blogs.nytimes.com/2016/02/17/which-type-of-exercise-is-best-for-the-brain/
------------------------end quotePHYS ED
Which Type of Exercise Is Best for the Brain?
By GRETCHEN REYNOLDS
FEBRUARY 17, 2016 5:45 AM---------------------------------------------------
Some forms of exercise may be much more effective than others at bulking up the brain, according to a remarkable new study in rats. For the first time, scientists compared head-to-head the neurological impacts of different types of exercise: running, weight training and high-intensity interval training. The surprising results suggest that going hard may not be the best option for long-term brain health.
As I have often written, exercise changes the structure and function of the brain. Studies in animals and people have shown that physical activity generally increases brain volume and can reduce the number and size of age-related holes in the brains white and gray matter.
Exercise also, and perhaps most resonantly, augments adult neurogenesis, which is the creation of new brain cells in an already mature brain. In studies with animals, exercise, in the form of running wheels or treadmills, has been found to double or even triple the number of new neurons that appear afterward in the animals hippocampus, a key area of the brain for learning and memory, compared to the brains of animals that remain sedentary. Scientists believe that exercise has similar impacts on the human hippocampus.
These past studies of exercise and neurogenesis understandably have focused on distance running. Lab rodents know how to run. But whether other forms of exercise likewise prompt increases in neurogenesis has been unknown and is an issue of increasing interest, given the growing popularity of workouts such as weight training and high-intensity intervals.
So for the new study, which was published this month in the Journal of Physiology, researchers at the University of Jyvaskyla in Finland and other institutions gathered a large group of adult male rats. The researchers injected the rats with a substance that marks new brain cells and then set groups of them to an array of different workouts, with one group remaining sedentary to serve as controls.
Some of the animals were given running wheels in their cages, allowing them to run at will. Most jogged moderately every day for several miles, although individual mileage varied.
Others began resistance training, which for rats involves climbing a wall with tiny weights attached to their tails.
Still others took up the rodent equivalent of high-intensity interval training. For this regimen, the animals were placed on little treadmills and required to sprint at a very rapid and strenuous pace for three minutes, followed by two minutes of slow skittering, with the entire sequence repeated twice more, for a total of 15 minutes of running.
These routines continued for seven weeks, after which the researchers microscopically examined brain tissue from the hippocampus of each animal.
They found very different levels of neurogenesis, depending on how each animal had exercised.
Those rats that had jogged on wheels showed robust levels of neurogenesis. Their hippocampal tissue teemed with new neurons, far more than in the brains of the sedentary animals. The greater the distance that a runner had covered during the experiment, the more new cells its brain now contained.
There were far fewer new neurons in the brains of the animals that had completed high-intensity interval training. They showed somewhat higher amounts than in the sedentary animals but far less than in the distance runners.
And the weight-training rats, although they were much stronger at the end of the experiment than they had been at the start, showed no discernible augmentation of neurogenesis. Their hippocampal tissue looked just like that of the animals that had not exercised at all.
Obviously, rats are not people. But the implications of these findings are provocative. They suggest, said Miriam Nokia, a research fellow at the University of Jyvaskyla who led the study, that sustained aerobic exercise might be most beneficial for brain health also in humans.
Just why distance running was so much more potent at promoting neurogenesis than the other workouts is not clear, although Dr. Nokia and her colleagues speculate that distance running stimulates the release of a particular substance in the brain known as brain-derived neurotrophic factor that is known to regulate neurogenesis. The more miles an animal runs, the more B.D.N.F. it produces.
Weight training, on the other hand, while extremely beneficial for muscular health, has previously been shown to have little effect on the bodys levels of B.D.N.F., Dr. Nokia said, which could explain why it did not contribute to increased neurogenesis in this study.
As for high-intensity interval training, its potential brain benefits may be undercut by its very intensity, Dr. Nokia said. It is, by intent, much more physiologically draining and stressful than moderate running, and stress tends to decrease adult hippocampal neurogenesis, she said.
These results do not mean, however, that only running and similar moderate endurance workouts strengthen the brain, Dr. Nokia said. Those activities do seem to prompt the most neurogenesis in the hippocampus. But weight training and high-intensity intervals probably lead to different types of changes elsewhere in the brain. They might, for instance, encourage the creation of additional blood vessels or new connections between brain cells or between different parts of the brain.
So if you currently weight train or exclusively work out with intense intervals, continue. But perhaps also thread in an occasional run or bike ride for the sake of your hippocampal health.
Posted by stan_the_man70 on February 20, 2016, at 15:11:07
In reply to A quick question... » stan_the_man70, posted by SLS on February 4, 2016, at 13:57:49
-------------------quote reference
http://www.cancure.org/choice-of-therapy
http://www.cancertutor.com/overview_of_best/
--------------------------------------endI don't know much about cancer
Pancreatic cancer is fast growing
Treat it like a stage IV cancer
(stop the growth of cancer cells, stop blood supply to cancer cells, eliminate cancer cells)Cancer supplements are generally healthy because if they can help against cancer should be vastly beneficial to others also
Supplements/herbs:
graviola (soursop)
curcumin (turmeric)
Indole-3-Carbinol/diindolylmethane (DIM) (for estrogen metabolism)
Bitter Raw Apricot Seeds (B17 Amygdalin)
Artemesia (sweet wormwood)
PectaSol-C (Modified Citrus Pectin)
Sulforaphane Glucosinolate (broccoli)
baking soda (alkaline)
flax seed with cottage cheeseOthers:
Essiac tea
Hoxsey
Pau D'Arco
Radium weed
Red Clover
Tian Xian
Boswellia Seratta
Olive Leaf ExtractAntioxidants amongst others:
green tea (EGCg)
vitamin D3 (sunlight)
SOD (wheat sprouts)immunity:
AHCC, maitake, Reishi, cordyceps
Astragalus
beta glucan
carrot juice
grapeseed extract (citricidal)Natural remedies protocol:
#1 Greens powder (Chlorella, Spirulina, Wheat Grass)
#2 Proteolytic Enzymes (Bromelain and Papain- advanced usage)
#3 Antioxidants (resveratrol, green tea, quercetin)Certain protocol:
curcumin (from turmeric), quercetin (from fruits like apples and from tea), resveratrol (from grape seed extract), spirulina extracts (C-phycocyanin combined with selenium), isoflavone (from soy) and indol-3 carbinol (from cruciferous vegetables like broccoli and cauliflower)The websites referenced above have many other protocols ranging from electromagnetic to cesium chloride.
-------------------------------------------------------------------
> What herbs or supplements are known to prevent or treat cancer?
>
> Specifically, someone I know has a precancerous cyst on her pancreatic duct (mucinous cystic neoplasm). I am hoping to find something that will slow-down or prevent its conversion to a malignant tumor.
>
> Thanks.
>
>
> - Scott
Posted by stan_the_man70 on February 21, 2016, at 12:52:16
In reply to Re: Hey B2chica, posted by B2chica on February 15, 2016, at 17:40:02
Hey, thanks for posting again...
saw your follow up msg...
hope things stabilize...> funny, i havent been here forever, until today.
> i am not doing well but i'll post more on that below.
> i do however greatly apprecaite the folowing suggestions..
>
> life- chaotic stability wise
> sleep varies from insomnia to hypersomnia
> weight-still going up.
> excercise- i got on the treadmill last week, then meds and lethargy kicked in and its all i can do to go from my rocking chair to my bed...
> diet-too much efffort to care. not eating much during day (no appitite) until about 10 at night than munch on whatever i find in the house
> ...anyway.
> its kinda nice to get a call-out. i really dont know too many people that care these days. ...or understand.
> thnx
> b2
>
>
> > hey b2chica how are you
> > how is life - how is sleep - how is weight - how is troubles
> > exercise - diet - work - social - all going fine if i may ask
> >
Posted by SLS on February 21, 2016, at 13:49:18
In reply to Cancer » SLS, posted by stan_the_man70 on February 20, 2016, at 15:11:07
Oh my God. I can't believe how much time you must have spent putting your post together. You are very generous. Thank you.
Fortunately, the results of my mother's biopsy were negative for malignancy and is not even pre-cancerous.
- Scott
This is the end of the thread.
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