Shown: posts 1 to 18 of 18. This is the beginning of the thread.
Posted by Jeroen on June 27, 2015, at 12:50:28
Hey everyone, i see a lot of misery on this planet
where i live now i'm okay but, i had a guy feeling i shoudnt get started 10 years ago with meds to treat psychosis, because there are people with harder problems in wheelchair, cancer, blindness..but i think i'm going down that road too now by taking the meds, i've taken almost any atypical even Clozapine, and that's a horse med,
if there is a God, which i believe it exists, some say no and some say do
it's so freaking complicated to get well, minocycline worked but i had to quit due to heart pains, IBS (still have it, caused by minocycline)is started to make me wonder
oh yes and i also smoke a marlboro from time to time now, it seems i cannot get better even there are therapies that cure but have dangerous side effects
Respect to all of you!
Jeroen
Posted by Tomatheus on June 27, 2015, at 15:57:09
In reply to Ok so please read this, Lou you too please, posted by Jeroen on June 27, 2015, at 12:50:28
> it's so freaking complicated to get well
Yes, it is. As helpful as the treatments that are currently available for mental conditions can be for some individuals, it is too bad that the treatments are oftentimes only so helpful for a lot of us. I tend to be optimistic about better days eventually being ahead for those of us with mental conditions, although I think that the most substantial of improvements to today's treatments aren't likely to come in the immediate future.
Tomatheus
Posted by SLS on June 27, 2015, at 16:05:53
In reply to Re: Ok so please read this, Lou you too please » Jeroen, posted by Tomatheus on June 27, 2015, at 15:57:09
> > it's so freaking complicated to get well
>
> Yes, it is. As helpful as the treatments that are currently available for mental conditions can be for some individuals, it is too bad that the treatments are oftentimes only so helpful for a lot of us. I tend to be optimistic about better days eventually being ahead for those of us with mental conditions, although I think that the most substantial of improvements to today's treatments aren't likely to come in the immediate future.
>
> Tomatheus
I'm thinking maybe gene therapy and epigenetic manipulations?
- Scott
Posted by Tomatheus on June 27, 2015, at 22:52:33
In reply to Treatments of the future? » Tomatheus, posted by SLS on June 27, 2015, at 16:05:53
> I'm thinking maybe gene therapy and epigenetic manipulations?
Yes, I tend to think that gene therapies and epigenetic manipulations do have some potential to be effective treatments for psychiatric disorders somewhere down the road. It might still be the case that the pharmaceutical companies will develop some more medications that would represent substantial advances over those that are currently used, but I tend to have my doubts as to whether the investigational medications currently in development will represent substantial advances if developed. Of course, a small advance in treatment is better than no advance, and even a treatment that could improve just one person's well being where other treatments might fail would be make a world of a difference for that one individual benefiting from the treatment. At the same time, it would be nice to see larger numbers of people with mental conditions helped by emerging treatments.
Tomatheus
Posted by hello123 on June 28, 2015, at 1:10:48
In reply to Re: Treatments of the future? » SLS, posted by Tomatheus on June 27, 2015, at 22:52:33
i figured oit would be at least 10 years away before Optogenetics would start being tested on humans. but according to this article, resrarchers hope to start testing Optogenetics on humans in about 2 years.
http://abc30.com/health/optogenetics-medicines-next-big-thing/626935/
Posted by hello123 on June 28, 2015, at 1:18:46
In reply to Re: Treatments of the future?, posted by hello123 on June 28, 2015, at 1:10:48
i suppose this new way to alter the functioning of neurons is why.
http://mcgovern.mit.edu/news/news/noninvasive-brain-control/
Posted by SLS on June 28, 2015, at 6:14:55
In reply to Re: Treatments of the future?, posted by hello123 on June 28, 2015, at 1:18:46
> i suppose this new way to alter the functioning of neurons is why.
> http://mcgovern.mit.edu/news/news/noninvasive-brain-control/I read about this awhile ago, but I didn't know they had moved so far beyond rat studies in proof-of-concept for use in humans.
- Scott
Posted by Lamdage22 on June 28, 2015, at 7:23:29
In reply to Re: Treatments of the future? » hello123, posted by SLS on June 28, 2015, at 6:14:55
Rapastinel seems like its worth a shot.
Although Scott you tried Ketamine without success so im not sure what that means for your response to Rapastinel?
Posted by SLS on June 28, 2015, at 8:16:10
In reply to Re: Treatments of the future?, posted by Lamdage22 on June 28, 2015, at 7:23:29
> Rapastinel seems like its worth a shot.
>
> Although Scott you tried Ketamine without success so im not sure what that means for your response to Rapastinel?I would not be optimistic were I to choose this drug.
I am MUCH more interested in hydroxynorketamine (HNK), a metabolite of ketamne. It is NOT a NMDA receptor blocker. This prevents dissociative and psychomimetic effects. It does, however, modulate nicotinic receptor activity and increases mTOR activity.
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1917666
The icing on the cake is that HNK is administered orally.
- Scott
Posted by Lamdage22 on June 28, 2015, at 8:26:23
In reply to Re: Treatments of the future? » Lamdage22, posted by SLS on June 28, 2015, at 8:16:10
Yes but it will take a long time unlike Rapastinel.
Supposedly Rapastinel doesnt have psychosis side effects.
Or do you think its a hoax that it doesnt cause them?
Posted by SLS on June 28, 2015, at 17:02:38
In reply to Re: Treatments of the future?, posted by Lamdage22 on June 28, 2015, at 8:26:23
> Yes but it will take a long time unlike Rapastinel.
>
> Supposedly Rapastinel doesnt have psychosis side effects.You are right.
> Or do you think its a hoax that it doesnt cause them?It is not a hoax.
Psychotomimetic and dissociative effects occur with ketamine because it attaches to and blocks the channel of the NMDA glutamate receptor.
Rapastinel attaches to a very different site of the NMDA receptor (glycine coreceptor) than does ketamine. Whereas ketamine completely blocks the glutamate channel, Rapastinel attaches off to the side and acts more as a modulator.
- Scott
Posted by Lamdage22 on June 28, 2015, at 22:43:56
In reply to Re: Treatments of the future? » Lamdage22, posted by SLS on June 28, 2015, at 17:02:38
> > Yes but it will take a long time unlike Rapastinel.
> >
> > Supposedly Rapastinel doesnt have psychosis side effects.
>
> You are right.
>
> > Or do you think its a hoax that it doesnt cause them?
>
> It is not a hoax.
>
> Psychotomimetic and dissociative effects occur with ketamine because it attaches to and blocks the channel of the NMDA glutamate receptor.
>
> Rapastinel attaches to a very different site of the NMDA receptor (glycine coreceptor) than does ketamine. Whereas ketamine completely blocks the glutamate channel, Rapastinel attaches off to the side and acts more as a modulator.
>
>
> - ScottGood.
Posted by bleauberry on July 6, 2015, at 11:40:54
In reply to Ok so please read this, Lou you too please, posted by Jeroen on June 27, 2015, at 12:50:28
I believe God is who He says He is in the Bible. I believe He loves each one of us as we love our own children. I believe His heart aches to see us suffer. I believe He wants us desperately to call out to Him for wisdom....which He promised He would freely give to all who ask....and within that wisdom are the roadmaps that get us better from our diseases, or give us some sort of peace and worth in living with them....all of which we cannot do for ourselves.
I believe the purpose of life is simply to walk with God, get to know God, and be with Him throughout the entire journey of being a made-of-dust earthly being. He wants us all to have the best experience. But most people keep God at arm's length or don't believe. Since God's people come to Him on purely a voluntary basis, we have to engage if we want Him.
That being said, He is aching for us to call on Him for every little thing we need! We should not be out trying to figure things out on our own, or relying on other humans to give it to us. We should be asking Him, daily, in the same way that we take in physical food each day, we also need His spirit with us everyday. When we ask Him all the time, daily, to fill us with His spirit and His wisdom....He knows our deepest thoughts and He will give us the info we need....whether it is a doctor's name, a medicine, a strategy, a way of life, whatever....He truly works in miraculous ways....answers do come to those who do not give up in asking.
We don't just eat a meal and then we are fine for the rest of the day, right? No. We need another meal. And a third one. And little ones inbetween.. It is the same with God....we need to continually refill His spirit....and it just requires asking.
Mino caused IBS because it knocked the balance of gut bacteria out of balance. Which was probably already way out of balance to begin with, didn't need much more to send it over the edge. All the medications, ya know?
Yogurt, Kefir, and/or probiotics taken on a daily basis can rebuild the gut flora and those symptoms go away.
I doubt you got IBS from such low doses and low time on Mino. It takes months and high doses to do that, and even then, will only happen to some people. You were on the right track I believe.
My personal opinion says a wheelchair, blindness, or cancer, are better than having a brain problem. Nothing is worse than depression, psychosis, or anxiety. I would take a wheelchair over them any day if I had to make a choice.
The guy you talked to didn't know what he was talking about.
God cured my Lyme disease. God does not walk around with a magic wand. So how did He do that? He pointed me to a magazine article....He pointed me to a stranger who happened to know a LLMD....He showed me a very low vitamin D lab test....He caused an MD to take a second look without me asking....He caused someone on Facebook to share an incredible piece of wisdom that was perfect for my treatment....He allowed lots of medicines and herbs to fail...that I would eventually get the message that was the wrong direction....I mean, every little tiny detail of 5 years, was Him. But I couldn't see it, any of it, until it had passed and I was looking back at it as history.
God heals for sure. He basically raised me from the dead. I think what confuses people is that He doesn't usually heal through miracles in modern day. He uses other humans and other things of the earth, intertwined into our lives at just the perfect time in the perfect places, custom just for us, super complicated, and when the dust settles, we realize it was not our own choice of medication that got us better, it wasn't the latest research we cherry picked as relevent, it was nothing we thought we did....it was Him causing us to do what we did, Him causing us to choose what we did....without Him we make the wrong choices....
Those are my views and I hold them very strongly. No doubt.
Jereon, logic and reason say one thing for sure.....the only substances that have offered you a glimpse of hope were....antibiotics. End of story. You want to get better? He gave you that bit of wisdom. Ignore it if you want, but I think that is a mistake.
Someone can take this any way they want to, but it is true that my recovery from chronic major depression did not begin in earnest until I opened my arms to God and I told Him it was ok if He took the steering wheel out of my hands. I knew that meant that the journey was probably going to go in a different direction that would be unknown and scary, and since that turned out to be Lyme, it was indeed unknown and scary....but I kept saying yes to the steering wheel because I knew my own driving for 20 years had not gotten me very far.
Best wishes, hang in there, talk to you again soon!
ps. all that said, miracle healings to happen sometimes....a lifetime schizophrenic in my church was instantly healed one Sunday....quite startling....quite amazing....almost scary actually...but it happened....my journey was more in line with everyone else at pbabble.
JL
Posted by Jeroen on July 6, 2015, at 12:20:12
In reply to Re: Ok so please read this, Lou you too please, posted by bleauberry on July 6, 2015, at 11:40:54
thanks, i've read your post
Amantadine (anti viral) 100 mg, minocycline 50 mg anti biotics, then those panotile (cipro) eardrops
all anti viral agents cured me temporary, made my condition better, finding myself again is a miracle, why would i ignore him, i hope everybody gets well one day
Posted by bleauberry on July 6, 2015, at 12:38:26
In reply to bleauberry, posted by Jeroen on July 6, 2015, at 12:20:12
Good to see you Jereon! Any new music lately?
You are such a strong fighter. I have faith in you. I've seen you so sick you could hardly understand a thing, hardly even make it through a day. But somehow in all of that horror you managed to lift yourself up, point your treatment in a new direction, an unconventional direction, a direction that showed you hope in places we don't usually look.
You're awesome! I've seen it. God knows it.
Posted by Jeroen on July 6, 2015, at 13:44:18
In reply to Re: bleauberry » Jeroen, posted by bleauberry on July 6, 2015, at 12:38:26
it's like crossing the warp 10 barrier in star trek : )
Posted by Jeroen on July 7, 2015, at 9:28:43
In reply to Re: bleauberry, posted by Jeroen on July 6, 2015, at 13:44:18
bleauberry it's definatelly a hidden infection in my brain, there's evidence
Panotile ear drops left and right, (anti biotic ciprofrolaxin in it) removed my psychosis in 2-3 days, i tried it 3 times afterwards and it didn't work, the second time did nothing, third time it made me psychotic and manic... so POOP out the hidden infection has regroupthen minocycline, first time worked like a charm but side, second time went psychotic and didnt work, third time extreme psychosis, fourth time caused some sort fo IBS syndrome ( i hope it's not cancer) if i quit my seroquel the pain become worse, so i am not doing that
then amantadine i only tried that once 100 mg, and had to quit because had psychotic symptoms but i felt better
wtf are we doing?????????maybe what I need is an super anti biotic for treatment resistant infections with no dangerous side effects????
Posted by bleauberry on July 11, 2015, at 16:50:59
In reply to to bleauberry poop out of anti biotics been having, posted by Jeroen on July 7, 2015, at 9:28:43
Too bad you couldn't get access to some supplements. Man I would be willing to bet Berberine would have you feeling some welcome surprising improvement within days or a few weeks. That's just one of several ideas I have found to be much more rewarding and reliable than others. Vitamin D? 5000IU a day? Vit C, 250mg to 500mg 3 times per day? Raw clove of garlic couple times a week? N-Acetyl-Cystein? If you can do any or all of those, I really think they have a place in your world. The NAC is to help your body make its own glutathione to help mop up toxins...which are the things actually causing the symptoms. Studies show it is sometimes used in psychiatry also. I take all of those every day. I decline if I stop any of them, so I know they are doing a good job.
Those ideas are specific for your presentation. Of all the herbs I can think of...a lot...I would place my best bets on berberine. I can only get it online though, so that isn't fair.
Barberry. Coptis. Goldenseal. Golden Root. Oregon graperoot. All of these plants have significant berberine in them.....grow your own garden! :-)
> bleauberry it's definatelly a hidden infection in my brain, there's evidence
>
>
> Panotile ear drops left and right, (anti biotic ciprofrolaxin in it) removed my psychosis in 2-3 days, i tried it 3 times afterwards and it didn't work, the second time did nothing, third time it made me psychotic and manic... so POOP out the hidden infection has regroup
>
> then minocycline, first time worked like a charm but side, second time went psychotic and didnt work, third time extreme psychosis, fourth time caused some sort fo IBS syndrome ( i hope it's not cancer) if i quit my seroquel the pain become worse, so i am not doing that
>
> then amantadine i only tried that once 100 mg, and had to quit because had psychotic symptoms but i felt better
>
>
> wtf are we doing?????????
>
> maybe what I need is an super anti biotic for treatment resistant infections with no dangerous side effects????
>
>
This is the end of the thread.
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