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Re: Treatments of the future? » Lamdage22

Posted by SLS on June 28, 2015, at 17:02:38

In reply to Re: Treatments of the future?, posted by Lamdage22 on June 28, 2015, at 8:26:23

> Yes but it will take a long time unlike Rapastinel.
>
> Supposedly Rapastinel doesnt have psychosis side effects.

You are right.

> Or do you think its a hoax that it doesnt cause them?

It is not a hoax.

Psychotomimetic and dissociative effects occur with ketamine because it attaches to and blocks the channel of the NMDA glutamate receptor.

Rapastinel attaches to a very different site of the NMDA receptor (glycine coreceptor) than does ketamine. Whereas ketamine completely blocks the glutamate channel, Rapastinel attaches off to the side and acts more as a modulator.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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