Posted by SLS on June 28, 2015, at 8:16:10
In reply to Re: Treatments of the future?, posted by Lamdage22 on June 28, 2015, at 7:23:29
> Rapastinel seems like its worth a shot.
>
> Although Scott you tried Ketamine without success so im not sure what that means for your response to Rapastinel?I would not be optimistic were I to choose this drug.
I am MUCH more interested in hydroxynorketamine (HNK), a metabolite of ketamne. It is NOT a NMDA receptor blocker. This prevents dissociative and psychomimetic effects. It does, however, modulate nicotinic receptor activity and increases mTOR activity.
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1917666
The icing on the cake is that HNK is administered orally.
- Scott
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poster:SLS
thread:1080020
URL: http://www.dr-bob.org/babble/20150520/msgs/1080038.html