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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by JawiCoolGuy on September 15, 2013, at 13:57:49
Nothing else. No co-morbid disorders, No concern over side effects. Just the most effective you know of for Treatment Resistant Depression
Posted by Topdog! on September 16, 2013, at 5:38:46
In reply to Best MAOI for TRD Depression, posted by JawiCoolGuy on September 15, 2013, at 13:57:49
Nardil!
..and as always,
Good luck!
Posted by Tomatheus on September 16, 2013, at 14:47:47
In reply to Best MAOI for TRD Depression, posted by JawiCoolGuy on September 15, 2013, at 13:57:49
JawiCoolGuy,
Nardil (phenelzine) and Parnate (tranylcypromine) tend to be more effective antidepressants than moclobemide. Marplan (isocarboxazid) hasn't been studied as extensively as Nardil and Parnate have. Selegiline, I think, is also likely to be less effective than Nardil and Parnate.
It's my understanding that only moclobemide (which is technically a "RIMA") and low-dose selegiline can be taken without following a restricted diet. With all of the other MAOIs, following a restricted diet is advised.
T.
Posted by sigismund on September 16, 2013, at 16:17:28
In reply to Best MAOI for TRD Depression, posted by JawiCoolGuy on September 15, 2013, at 13:57:49
How about Marplan?
Posted by bleauberry on September 16, 2013, at 16:54:28
In reply to Best MAOI for TRD Depression, posted by JawiCoolGuy on September 15, 2013, at 13:57:49
Nardil or Parnate, flip a coin. Nardil has the rougher side effects I think.
As a side comment, I don't buy the notion of TRD. If psychiatric drugs have not improved the condition, it doesn't mean it is treatment resistant. It means the wrong treatments were applied. It means the assumption the neurotransmitters were messed up was maybe a wrong assumption, and that the problem is something else not being touched by the ADs.
That's why I personally think it is important for all psych patients, priority to the sickest, to research online and learn all about things such as lyme disease and toxins in our lifestyle and what plants, herbs, foods, are specifically potent for things like unsuspected inflammation, unsuspected pathogen load, unsuspected toxin load. If those 3 areas are cleaned up, psych symptoms improve often dramatically. The reason a somewhat wide umbrella is needed, I think, is because within it are the most common things I know of that cause the type of depression that responds negatively or neutrally to psych meds.
This is the end of the thread.
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Dr. Bob is Robert Hsiung, MD,
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