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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Bekka H. on April 10, 2002, at 18:19:58
Has anyone here ever taken Cylert/Pemoline? I understand that it is not a "first choice" drug due to possible liver problems, but I'd be interested to hear from anyone who has taken it. If you have tried it, how long did you use it? How did it compare with other pstims? Why did you stop taking it? Did you take it with any other medications, including antidepressants?
Thanks for your help.
Bekka
Posted by dennison on April 10, 2002, at 22:24:56
In reply to Cylert/Pemoline questions, posted by Bekka H. on April 10, 2002, at 18:19:58
Hi Bekka I've taken cylert for several years the liver tests are no big deal everyone has been just fine. Cylert I'd rate about a 2 or 3 on a scale of 10 it sometimes provides a minor lift in energy but many times it makes me drowsy and isn't worth dirt. Actually ritalin wasn't much better, but the ritalin was considerably easier to tolerate, cylert can cause an awful lot of tension and discomfort many times. Dexedrine far outclassed ritalin and cylert simply is a placebo compared to dexedrine. Cylert does have one advantage though can't say I've ever experienced even the slightest crash or letdown on it, unless I hadn't taken it for at least a couple of days. On the otherhand if you think you can take cylert and a 1/2 hr. to 45 minutes latter you're going to feel a sense of energy it just isn't likely to happen. It has a very mild stimulant action and you kind of have to already be up and going for it to work. Taking it before noon almost always makes me ache to lay back down, latter in day perhaps it might provide a mild boost......................................................................I've taken the last few yrs. with parnate and effexor and prozac.
Posted by Bekka H. on April 10, 2002, at 23:35:24
In reply to Re: Cylert/Pemoline questions » Bekka H., posted by dennison on April 10, 2002, at 22:24:56
Hi Dennison,
Thank you for your help! I've never taken Cylert, but I have taken Ritalin in several of its forms and Dexedrine. Ritalin feels like a "let down" if I've been on Dexedrine for a while, but if I stay off of Dex for a week or two and then try Ritalin, it's not so bad. The longer I stay off of Dex, the easier it is to see benefits of Ritalin. I do think that when I stop Dex, there is a definite withdrawal period.
Bekka
Posted by Elizabeth on April 11, 2002, at 12:07:31
In reply to Cylert/Pemoline questions, posted by Bekka H. on April 10, 2002, at 18:19:58
Hi. I took Cylert for a few months (somewhere between 6 and 12) while I was in college. I thought it was pretty good. It helped with my mood as well as my ability to focus, and it lifted the fog (so to speak). It also helped me regulate my sleep -- it prevented me from napping during the day, then I would get tired as it was wearing off (right at the end of the day) and sleep all through the night. It didn't have the "roller-coaster" effect that sometimes goes along with short-acting drugs (such as Ritalin and Dexedrine). I could skip a day or not take it on the weekend and I was still okay. It was mild but effective and didn't have any side effects. And my liver was just fine (although at the time it didn't have the black box warning).
-elizabeth
Posted by Bekka H. on April 11, 2002, at 21:22:16
In reply to Re: Cylert/Pemoline questions, posted by Elizabeth on April 11, 2002, at 12:07:31
> Hi. I took Cylert for a few months (somewhere between 6 and 12) while I was in college. I thought it was pretty good. It helped with my mood as well as my ability to focus, and it lifted the fog (so to speak). It also helped me regulate my sleep --It didn't have the "roller-coaster" effect that sometimes goes along with short-acting drugs (such as Ritalin and Dexedrine). It was mild but effective and didn't have any side effects. >
> -elizabeth*************************************************
Hi Elizabeth. Thank you for your reply. You said that Cylert didn't have the roller-coaster effect that sometimes goes along with short-acting drugs like Dex and Ritalin. Is Cylert a long-acting drug (time release)? When you were on it, did you combine it with any other meds? Was it the first medicine in its class that you had ever taken? The reason I ask is that Dexedrine was the first pstim I ever took, and I found it very difficult to switch to Ritalin after Dex. I've often thought that if I'd started with Ritalin, it would have been easier than trying to switch from Dex to Ritalin. Whenever I have made the switch from Dex to Rit, it takes a good one to two weeks of Dex-withdrawal before I can really see what Ritalin is doing on its own.
Thanks again.
Bekka
Posted by Elizabeth on April 16, 2002, at 21:44:13
In reply to Cylert/Pemoline questions- Elizabeth, posted by Bekka H. on April 11, 2002, at 21:22:16
Hi Bekka. Sorry it's taken me so long to write -- I took a break from PB for a few days (for various reasons).
> You said that Cylert didn't have the roller-coaster effect that sometimes goes along with short-acting drugs like Dex and Ritalin. Is Cylert a long-acting drug (time release)?
It's not a controlled-release formulation, no; it's just a naturally long-acting drug.
It does seem like a lot of people find it ineffective -- especially people who've used Ritalin or Dexedrine before. Also, it's not clear whether Cylert has a similar mechanism of action to these other stimulants. (BTW, amphetamine has at least one mechanism that Ritalin doesn't have; this might be part of the reason you had trouble switching over. Cylert probably would not "cover" for amphetamine withdrawal, either.)
> When you were on it, did you combine it with any other meds?
No, just the Cylert.
> Was it the first medicine in its class that you had ever taken?
The first psychostimulant, you mean? Yes. I did subsequently try some other ones, but they caused problems with the MAOI that I was on at the time.
I hope this helps. Good luck, whatever you decide to do.
-elizabeth
Posted by Bekka H. on April 16, 2002, at 22:00:19
In reply to Re: Cylert/Pemoline » Bekka H., posted by Elizabeth on April 16, 2002, at 21:44:13
(BTW, amphetamine has at least one mechanism that Ritalin doesn't have; this might be part of the reason you had trouble switching over. Cylert probably would not "cover" for amphetamine withdrawal, either.)
> -elizabeth*************************************************
Hi Elizabeth,
Thank you for your reply. By the way, when you say that amphetamine has at least one mechanism of action that Ritalin doesn't have, are you referring to the release of neurotransmitters versus Ritalin's blocking the reuptake, or did you mean something else altogether?
Bekka
Posted by Temoigneur on August 31, 2002, at 0:34:53
In reply to Re: Cylert/Pemoline questions » Bekka H., posted by dennison on April 10, 2002, at 22:24:56
Hi I was wondering if you had any knowledge of Cylert being used for OCD. Also you say you're still on it, how do you get the drug?
Posted by Temoigneur on August 31, 2002, at 0:42:44
In reply to Re: Cylert/Pemoline » Bekka H., posted by Elizabeth on April 16, 2002, at 21:44:13
> Hi Bekka. Sorry it's taken me so long to write -- I took a break from PB for a few days (for various reasons).
>
> > You said that Cylert didn't have the roller-coaster effect that sometimes goes along with short-acting drugs like Dex and Ritalin. Is Cylert a long-acting drug (time release)?
>
> It's not a controlled-release formulation, no; it's just a naturally long-acting drug.
>
> It does seem like a lot of people find it ineffective -- especially people who've used Ritalin or Dexedrine before. Also, it's not clear whether Cylert has a similar mechanism of action to these other stimulants. (BTW, amphetamine has at least one mechanism that Ritalin doesn't have; this might be part of the reason you had trouble switching over. Cylert probably would not "cover" for amphetamine withdrawal, either.)
>
> > When you were on it, did you combine it with any other meds?
>
> No, just the Cylert.
>
> > Was it the first medicine in its class that you had ever taken?
>
> The first psychostimulant, you mean? Yes. I did subsequently try some other ones, but they caused problems with the MAOI that I was on at the time.
>
> I hope this helps. Good luck, whatever you decide to do.
>
> -elizabeth
Hi elizabeth, I heard that Cylert can be helpful for people who have fatigue, and OCD - ritalin and dexedrine make my OCD worse, I'm using modafanil right now, but I seem to be gaining tolerance, and I need something that will enable me to function as I'm in school and take zyprexa and effexor, which make me tired. Would you be able to tell me how I could go about obtaining Clyert as it is no longer on the marketThanks so much
Ben
Posted by Temoigneur on August 31, 2002, at 0:46:09
In reply to Cylert/Pemoline questions, posted by Bekka H. on April 10, 2002, at 18:19:58
> Has anyone here ever taken Cylert/Pemoline? I understand that it is not a "first choice" drug due to possible liver problems, but I'd be interested to hear from anyone who has taken it. If you have tried it, how long did you use it? How did it compare with other pstims? Why did you stop taking it? Did you take it with any other medications, including antidepressants?
>
> Thanks for your help.
>
> BekkaHi Bekka, I have to take a pstim but ritalin and dexadrine make my OCD worse, I've heard Cylert doesn't do this. What's your experience with cylert, how does one go about obtaining it now that it's no longer on the market. I ask like this because I'm in school, and fear I'm gaining tolerance to modafinil, I need something I can switch to if that's what's happening
Thanks
Ben
Posted by fairnymph on August 31, 2002, at 16:32:30
In reply to Re: Cylert/Pemoline - Elizabeth, posted by Bekka H. on April 16, 2002, at 22:00:19
> (BTW, amphetamine has at least one mechanism that Ritalin doesn't have; this might be part of the reason you had trouble switching over. Cylert probably would not "cover" for amphetamine withdrawal, either.)
> > -elizabeth
>
> *************************************************
>
> Hi Elizabeth,
>
> Thank you for your reply. By the way, when you say that amphetamine has at least one mechanism of action that Ritalin doesn't have, are you referring to the release of neurotransmitters versus Ritalin's blocking the reuptake, or did you mean something else altogether?
>
> Bekka
>I believe that is what Elizabeth meant.
Amphetamine cause the release of catecholamine as well as block the reuptake of them, while methylphenidate (ie ritalin)only inhbits reuptake.
~fairnymph
Posted by Phil Kolber on January 2, 2012, at 13:24:38
In reply to Re: Cylert/Pemoline questions, posted by Temoigneur on August 31, 2002, at 0:46:09
> > Has anyone here ever taken Cylert/Pemoline? I understand that it is not a "first choice" drug due to possible liver problems, but I'd be interested to hear from anyone who has taken it. If you have tried it, how long did you use it? How did it compare with other pstims? Why did you stop taking it? Did you take it with any other medications, including antidepressants?
> >
> > Thanks for your help.
> >
> > Bekka
>
> Hi Bekka, I have to take a pstim but ritalin and dexadrine make my OCD worse, I've heard Cylert doesn't do this. What's your experience with cylert, how does one go about obtaining it now that it's no longer on the market. I ask like this because I'm in school, and fear I'm gaining tolerance to modafinil, I need something I can switch to if that's what's happening
>
> Thanks
>
> BenI have taken Cylert/Pemoline for 23 years with no problem and good teselts.
This is the end of the thread.
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