Psycho-Babble Medication Thread 970877

Shown: posts 1 to 11 of 11. This is the beginning of the thread.

 

Phenelzine + Nortriptaline advice please?

Posted by Frequent Fryer on November 20, 2010, at 22:21:24

Would it be ok to take my Nortriptaline with my Nardil all at once in the mourning. I always forget to take it at night and don't find the Histaminergic effects very sedating?

 

Re: Phenelzine + Nortriptaline advice please?

Posted by morgan miller on November 20, 2010, at 22:56:46

In reply to Phenelzine + Nortriptaline advice please?, posted by Frequent Fryer on November 20, 2010, at 22:21:24

There could be more of an interaction between the two, like one of them increasing the levels of another more than they do when taking at separate times. Someone with more knowledge of these two medications would have to weigh in.

As far as just taking Nortriptyline in the morning goes, if you don't think it is sedating you, I don't see why it would be an issues to just take it in the morning. Like I said, the only reason to maybe be concerned about taking it in the morning is if the interaction between it and Nardil is intensified by taking them together.

 

Re: Phenelzine + Nortriptaline advice please? » Frequent Fryer

Posted by SLS on November 21, 2010, at 6:33:00

In reply to Phenelzine + Nortriptaline advice please?, posted by Frequent Fryer on November 20, 2010, at 22:21:24

> Would it be ok to take my Nortriptaline with my Nardil all at once in the mourning.

One can take nortriptyline as one dose. If you find that side effects do not present a problem taking it this way, I would not be so concernted about precipitating a serious interaction between nortriptyline and Nardil. Just be aware that if low blood pressue becomes a problem, you may have to take the nortriptyline all at once at night. I would be cautious about taking all of your Nardil at once. I take mine three times a day. However, twice a day would probably work fine. I would recommend taking Nardil in the morning and afternoon. It will help prevent an overly acute change in MAO activity and side effects. You might actually feel an intrusion of depression at the end of your dosing period. This is only a guess on my part. I can't produce any proof that this will happen. Perhaps you can divide dosing of both drugs morning and afternoon. If you are compelled to take all of your medication in the morning, please post describing your experience. It would be very helpful.

Good luck.


Currently:

Nardil 90mg (30mg t.i.d.)
nortriptyline 150mg (50mg t.i.d)
Lamictal 200mg (100mg b.i.d.)


- Scott

 

Re: Phenelzine + Nortriptaline advice please?

Posted by Conundrum on November 21, 2010, at 12:18:26

In reply to Re: Phenelzine + Nortriptaline advice please? » Frequent Fryer, posted by SLS on November 21, 2010, at 6:33:00

Scott, is your combo helping?
>
> Currently:
>
> Nardil 90mg (30mg t.i.d.)
> nortriptyline 150mg (50mg t.i.d)
> Lamictal 200mg (100mg b.i.d.)
>
>
> - Scott
>
>

 

Re: Phenelzine + Nortriptaline advice please? » Conundrum

Posted by SLS on November 21, 2010, at 17:17:10

In reply to Re: Phenelzine + Nortriptaline advice please?, posted by Conundrum on November 21, 2010, at 12:18:26

Hi.

> Scott, is your combo helping?

Thanks for asking.

It does help some, but not nearly enough to get me back to work. When I first added agomelatine, I experienced a brief robust improvement lasting 3 days. It is always the same old story with me. 3 days. I can't imagine what might possibly be happening so rapidly in the brain physiologically to produce such a quick relapse. There is a clue hidden somewhere within those 3 days.

What I have decided to do is to remain on the three drugs I am currently taking so that I can function well enough to live independently. I will try different treatments as they become available. I have all but exhausted those that currently exist. Tianeptine I have not tried. I would not combine it with an MAOI without evidence proving that it can be done safely. I am growing more and more interested in rTMS. Unfortunately, I will probably have to wait until Medicare covers it, if it ever does.

> > Currently:
> >
> > Nardil 90mg (30mg t.i.d.)
> > nortriptyline 150mg (50mg t.i.d)
> > Lamictal 200mg (100mg b.i.d.)


- Scott

 

Re: Phenelzine + Nortriptaline advice please? » SLS

Posted by ed_uk2010 on November 21, 2010, at 18:01:55

In reply to Re: Phenelzine + Nortriptaline advice please? » Conundrum, posted by SLS on November 21, 2010, at 17:17:10

Hi Scott,

Could you combine tianeptine with nortriptyline and Lamictal? I don't know whether it's safe.


 

Re: Phenelzine + Nortriptaline advice please? » ed_uk2010

Posted by SLS on November 21, 2010, at 18:30:48

In reply to Re: Phenelzine + Nortriptaline advice please? » SLS, posted by ed_uk2010 on November 21, 2010, at 18:01:55

Hi Ed.

> Could you combine tianeptine with nortriptyline and Lamictal? I don't know whether it's safe.

It sounds safe to me. That would be a good plan.

Thanks.


- Scott

 

Re: Phenelzine + Nortriptaline advice please? » SLS

Posted by ed_uk2010 on November 22, 2010, at 16:14:43

In reply to Re: Phenelzine + Nortriptaline advice please? » ed_uk2010, posted by SLS on November 21, 2010, at 18:30:48

> Hi Ed.
>
> > Could you combine tianeptine with nortriptyline and Lamictal? I don't know whether it's safe.
>
> It sounds safe to me. That would be a good plan.

Just a thought. I don't know whether it would help, but it could be worth considering.

 

Re: Phenelzine + Nortriptaline advice please? » SLS

Posted by Conundrum on December 28, 2010, at 23:52:34

In reply to Re: Phenelzine + Nortriptaline advice please? » Conundrum, posted by SLS on November 21, 2010, at 17:17:10

sorry for the late reply. Not sure why I didn't reply before, I'm sure I did in my head. What are your main symptoms. I've seen you've been here before me, so I don't think I don't know what you are trying to get rid of, but judging by the meds it sounds like a treatment resistant MDD.
> Hi.
>
> > Scott, is your combo helping?
>
> Thanks for asking.
>
> It does help some, but not nearly enough to get me back to work. When I first added agomelatine, I experienced a brief robust improvement lasting 3 days. It is always the same old story with me. 3 days. I can't imagine what might possibly be happening so rapidly in the brain physiologically to produce such a quick relapse. There is a clue hidden somewhere within those 3 days.
>
> What I have decided to do is to remain on the three drugs I am currently taking so that I can function well enough to live independently. I will try different treatments as they become available. I have all but exhausted those that currently exist. Tianeptine I have not tried. I would not combine it with an MAOI without evidence proving that it can be done safely. I am growing more and more interested in rTMS. Unfortunately, I will probably have to wait until Medicare covers it, if it ever does.
>
> > > Currently:
> > >
> > > Nardil 90mg (30mg t.i.d.)
> > > nortriptyline 150mg (50mg t.i.d)
> > > Lamictal 200mg (100mg b.i.d.)
>
>
> - Scott

 

Re: Phenelzine + Nortriptaline advice please? » Conundrum

Posted by SLS on December 29, 2010, at 7:10:58

In reply to Re: Phenelzine + Nortriptaline advice please? » SLS, posted by Conundrum on December 28, 2010, at 23:52:34

> sorry for the late reply. Not sure why I didn't reply before, I'm sure I did in my head. What are your main symptoms. I've seen you've been here before me, so I don't think I don't know what you are trying to get rid of, but judging by the meds it sounds like a treatment resistant MDD.

Hi.

I am pretty sure that I have an unusual form of biplar disoder. People like me, who have experienced various presentations of episodes like me who never experience spontaneous manic breakthroughs, usually in conjunction with and are left to languish in a state of perpetual psychic pain along with major cognitive dysfuntion. Major Depressive Disorder and the depression associated with a bipolar diathesis look very similar. Yet, it is important to not characterize both MDD and BD and being manifestations of the same disease. Since the ealy 1995treat these patients differently than bipolar disorder.

You should start a thread regading how many people have ever been rapid cyclers (4 or more affective episodes per year) Of these people, you can get a count of how many people are currently experiencing. To witness Rapid cyclicity is to witness a dramatic precipation mood swing that occurs incdependant of environmental

Interestingly, rapid cyclicity does not have to be a stable and pervasive indefinitely. Cycling sometimes drifts or can appear for the first time. Rapid cyclicity occurs more often in females. Rapid cycling can sometime be abolished using drugs like lithium or perhaps agomelatine.


- Scott

 

Re: Phenelzine + Nortriptaline advice please? » SLS

Posted by Conundrum on December 29, 2010, at 16:16:45

In reply to Re: Phenelzine + Nortriptaline advice please? » Conundrum, posted by SLS on December 29, 2010, at 7:10:58

So what do your episodes look like when you have them?
>
> I am pretty sure that I have an unusual form of biplar disoder. People like me, who have experienced various presentations of episodes like me who never experience spontaneous manic breakthroughs, usually in conjunction with and are left to languish in a state of perpetual psychic pain along with major cognitive dysfuntion. Major Depressive Disorder and the depression associated with a bipolar diathesis look very similar. Yet, it is important to not characterize both MDD and BD and being manifestations of the same disease. Since the ealy 1995treat these patients differently than bipolar disorder.


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