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Dr. Bob is Robert Hsiung, MD,
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Posted by NewQuestions on March 30, 2009, at 13:36:23
In reply to Re: most POTENT AD for resistant anxiety+depressio » NewQuestions, posted by michael45 on March 30, 2009, at 11:09:07
How long did they work before poop out?
Posted by michael45 on March 30, 2009, at 14:13:03
In reply to Re: most POTENT AD for resistant anxiety+depressio, posted by NewQuestions on March 30, 2009, at 13:36:23
lexapro was the only AD that ever worked and it only worked for a month..
and the beznos only work a week or so then my tolerance goes way up and it becomes pointless..when i go to the doctor asking for a higher dose..it just gives a red flag for addiction and that im just trying to get more drugs
so that method of benzos doesnt work
Posted by NewQuestions on March 30, 2009, at 14:25:44
In reply to Re: most POTENT AD for resistant anxiety+depressio » NewQuestions, posted by michael45 on March 30, 2009, at 14:13:03
that does not sound like tolerance or poop out... that sounds like the drugs never really worked to begin with... if you are bipolar, a mood stablizer might work like lamictal
Posted by Neal on March 30, 2009, at 16:10:28
In reply to Re: most POTENT AD for resistant anxiety+depression??? » Neal, posted by michael45 on March 29, 2009, at 6:58:59
_
Michael,
Answering your question on Sinequan (doxepin). When I first took it, I was in extemely bad shape, and it did turn things around. I took it for years. It helps with anxiey, sleep and depression. Morning sedation can be a problem with it, that might be controlled by either raising or lowering the dose. It's been years since I took it, so I can't remember which, but a search of past posts would clue you in.
I forgot that Effexor was amazing for me, turning around a bad situation in a matter of a week or so. But it's an SSRI, with all the side-effects of SSRI's, the worst is sexual numbness for some people.
Let me know if you have further questions. Sorry that I can't remember more about the dosing of the doxepin. I think it can be as low as 25mg, or as high as 300mg./day
Effexor for me is 75mg 2x/day.
Hope this helps
~Neal
Posted by metric on March 31, 2009, at 16:57:07
In reply to most POTENT AD for resistant anxiety+depression???, posted by michael45 on March 27, 2009, at 21:31:39
> okay well i have this horrible tension feeling combined with this killer depression and im about to admit myself into a hospital if i cant figure this out soon...
>
> ive tried:
> -lexapro- worked:] then pooped out:[
> -prozac- numbed me out, felt horrible
> -zoloft- felt even worse
> -cymbalta- no change, felt horrible
> -wellbutrin- made me super agitated
> -lamictal- made me feel super agitated and horrible
> -klonopin- helped for a week for anxiety (then tolerance started to kick in) but made depression worse
> -ativan- made me tired, but didnt do s*** for anxiety? wow haha
> -trazodone- barley did anything for sleep and nothing for anything else
>
>
>
> ...im going to the shrink this week and dont know what to try next...im getting pretty desperate and will even try shock therapy (ECT) if that will help hah.. seriously!
>
> what are good antidepressants that work well for both anxiety + depression..forget about all that ssri/snri bull**** or anything like those..
>
> i need some top of the line potent stuff...MAOIs? remeron? maybe even the crude TCAs? idk whats works good for you guys???
>
>
> pleaee helpp out!!
>
Fentanyl+Desoxyn would be a much better choice than ECT (in terms of both safety and effectiveness), but you won't in a million years get a doctor to prescribe that to you for depression (not his fault -- he would at the very least be putting his license at risk).Your best bet is probably to "augment" a traditional antidepressant with a CNS stimulant and/or benzodiazepine. You could also try Provigil+Xanax (modafinil and alprazolam, respectively) if none of the traditional ADs are tolerable/effective.
Posted by michael45 on April 1, 2009, at 1:34:05
In reply to Re: most POTENT AD for resistant anxiety+depressio » michael45, posted by metric on March 31, 2009, at 16:57:07
by traditional AD do you mean just an ssri? or?
thanks for everything:]
Posted by michael45 on April 1, 2009, at 1:35:03
In reply to Re: most POTENT AD for resistant anxiety+depression???, posted by Neal on March 30, 2009, at 16:10:28
i might mention this one to the doctor...thankyou for your help
and if you have any other natural supplements or anything lemme know
thanks:]
Posted by michael45 on April 1, 2009, at 1:36:10
In reply to Re: most POTENT AD for resistant anxiety+depressio, posted by NewQuestions on March 30, 2009, at 14:25:44
lamictal seemed to make me have anger outburts and agitiation even more on top of the depression
my guess is that i need something like seroquel+nardil?
Posted by michael45 on April 1, 2009, at 1:37:51
In reply to Re: most POTENT AD for resistant anxiety+depression???, posted by Meltingpot on March 30, 2009, at 13:18:18
i have not tried that yet..i read the weight gain is bad though
but one question when you take it does it make you feel blissful and happy (or at least content)
and does it give you a sterotype antipychiotic zombie personality
Posted by michael45 on April 1, 2009, at 1:40:14
In reply to Re: most POTENT AD for resistant anxiety+depression???, posted by bleauberry on March 29, 2009, at 9:17:01
can you please give me your brief emotional experience on Parnate, Nardil, and Clomipramine
(i wanna get my personality back and not become a zombie and i hear alot of AD or antipsychitics do that)
do these bring you back and make you feel content and alive?
Posted by michael45 on April 1, 2009, at 1:41:31
In reply to Re: most POTENT AD for resistant anxiety+depressio, posted by NewQuestions on March 30, 2009, at 9:27:27
i can tolerate drugs..now that i think of it
just my body is super resistant to anything i out in it..anything alcohol, benzo, Ads, acne medications, anything haha..just to clarify
Posted by michael45 on April 1, 2009, at 1:45:09
In reply to Re: most POTENT AD for resistant anxiety+depression???, posted by desolationrower on March 28, 2009, at 22:40:40
hey desolationrower your link was very helpful
i feel like some of the symptoms it decribed...if i am some type of bipolar and i took an antipsychotic like seroquel or zyprexa wouldnt just make me a zombie..i mean i want my personality back and dont those meds like seroquel block neurotrasmitters to numb you out alot
idk maybe a good combo would be seroquel+nardil??
Posted by michael45 on April 1, 2009, at 1:46:32
In reply to Re: most POTENT AD for resistant anxiety+depression???, posted by desolationrower on March 28, 2009, at 22:40:40
hey desolationrower your link was very helpful
i feel like some of the symptoms it decribed...if i am some type of bipolar and i took an antipsychotic like seroquel or zyprexa wouldnt just make me a zombie..i mean i want my personality back and dont those meds like seroquel block neurotrasmitters to numb you out alot
idk maybe a good combo would be seroquel+nardil??
Posted by Jody Post on April 1, 2009, at 2:42:52
In reply to Re: most POTENT AD for resistant anxiety+depression??? » desolationrower, posted by michael45 on April 1, 2009, at 1:46:32
Posted by Jody Post on April 1, 2009, at 2:46:36
In reply to Re: most POTENT AD for resistant anxiety+depressio » NewQuestions, posted by michael45 on April 1, 2009, at 1:41:31
> i can tolerate drugs..now that i think of it
>
> just my body is super resistant to anything i out in it..anything alcohol, benzo, Ads, acne medications, anything haha..just to clarifyGod will help you live your life
Posted by desolationrower on April 1, 2009, at 3:17:54
In reply to Re: most POTENT AD for resistant anxiety+depression??? » desolationrower, posted by michael45 on April 1, 2009, at 1:46:32
well, theres only one way to really find out what will work for you, but i think clarifying the bipolar would be a good idea when deciding on whether to start an AP or AD first. if you are taking meds availible in the states, for you bipolar i guess i'd suggest ziprasidone or abilify first, since they are pretty low on the long-term side effects, although probably not quite as effective. i guess i'd try valproate next. if the mood stabilizer gets rid of some of the 'anxiety' stuff but isn't doing much for depression, you could add an maoi.
-d/r
Posted by michael45 on April 1, 2009, at 3:24:22
In reply to Re: most POTENT AD for resistant anxiety+depressio, posted by Jody Post on April 1, 2009, at 2:46:36
you know you make a good point..
but im going through so much pain everyday i think about blowing off my head with my 12 gauge in my garage..
i know i pray and cry out to God every single day..and i read Psalms ,Proverbs, and Ecclesiastes all to help give me some help and hope...i honestly have something wrong in my brain...i dont see why God would create such a work of art as a human being and make them feel so terrible they end up killing thenselves..i do trust in God alot..but the way i look at it, is that God will provide by helping me by working through the medications and doctorshope you catch my drift..thanks for your input though
Posted by michael45 on April 1, 2009, at 3:28:18
In reply to Re: most POTENT AD for resistant anxiety+depression???, posted by desolationrower on April 1, 2009, at 3:17:54
okay thanks for all the help d/r
you have been the most helpful so far
im gonna print this out and casually tell the doctor what me and my friends (you lol) talked about what could help by doing an AP with an MAOI
i know hes the doctor and makes the deceisions but you seem to know your stuff..and bring up some good points..thankyou
:] << (hopefully haha)
Posted by desolationrower on April 1, 2009, at 3:51:06
In reply to Re: most POTENT AD for resistant anxiety+depression??? » desolationrower, posted by michael45 on April 1, 2009, at 1:46:32
'zombification' is certainly waht happens most people who take these, but sometimes what they numbe is all the anxiety and irritablity. its sort of circular, but if you do have bipolar, they'll probably help, and if you're just depressed+anxious you'll feel about the same only more numb. which is why thinking carfully about if your symptoms match bipolar is worth doing
-d/r
Posted by desolationrower on April 1, 2009, at 4:03:45
In reply to Re: most POTENT AD for resistant anxiety+depression??? » desolationrower, posted by michael45 on April 1, 2009, at 3:28:18
good luck
and really, the part of the bible about feeling cursed in Job. not sure i'd want to read that _while_ depressed though, maybe stick to contemplating god's love and praying for kindness to others.
don't overlook anticonvulsatns for bipolar, valproate is quite good for mixed states and might help anxiety too.
-d/r
Posted by garnet71 on April 1, 2009, at 7:18:26
In reply to Re: most POTENT AD for resistant anxiety+depressio » Jody Post, posted by michael45 on April 1, 2009, at 3:24:22
Michael - please give the handgun to a friend until you find an effective treatment. It would only be just temporary.
When you are testing out meds, you can't predict how they will effect your mood, which they can change w/in a day or two.
PLEASE - my son's aunt had a handgun in the house and ended up shooting herself in the head with a just a few days after she started Prozac. She wasn't having suicidal thoughts before, but started the Prozac and complained she was feeling off. Her daughter found her like that in the morning.
It could happen to anyone. Now if someone sought out to commit suicide, they could find other ways, but using a handgun entails less thinking and planning, and just having it in the house increases the chances. Even if you were just saying that in a joking way, you obviously are aware of the handgun, and even at times things in our subconscious could manifest w/o our 'consent'.
Posted by metric on April 1, 2009, at 17:05:59
In reply to Re: most POTENT AD for resistant anxiety+depressio » metric, posted by michael45 on April 1, 2009, at 1:34:05
> by traditional AD do you mean just an ssri? or?
>I mean nominal antidepressants -- drugs bearing the distinction of "antidepressant" by having been placed in the artificial category of "antidepressant" (chemicals that relieve depression without elevating mood) by the FDA or respective regulatory agency of your country (if outside the U.S.).
Perhaps something like venlafaxine (Effexor XR) + d-amphetamine (DextroStat, Dexedrine) + clonazepam (Klonopin). Nardil + d-amphetamine would probably be more effective but harder to obtain.
> thanks for everything:]
Posted by metric on April 1, 2009, at 17:17:36
In reply to Re: most POTENT AD for resistant anxiety+depression??? » desolationrower, posted by michael45 on March 29, 2009, at 7:28:24
> no i dont really have bipolar symptoms..i feel the same all day longg
> ...im in a constant state of agitated major depression with some anxiety..its like feeling super depressed but at the same time feeling an intense feeling of inner restlessness...sucks A**
>After reading some more of your messages, I'd like to retract my suggestion of stimulants. Have you tried mirtazapine (Remeron)? It can help with your somatic complaints and tension.
Posted by michael45 on April 3, 2009, at 0:13:52
In reply to Re: most POTENT AD for resistant anxiety+depression???, posted by desolationrower on April 1, 2009, at 4:03:45
do you think depakote+maoi inhibitor would be a good anxiety/depression/ mood stabilizer combo
Posted by michael45 on April 3, 2009, at 0:14:39
In reply to Re: most POTENT AD for resistant anxiety+depressio » michael45, posted by metric on April 1, 2009, at 17:17:36
i know remeron helps with some anxiety and depression..but do you would think it would help with constant tension??
jw our thoughts?
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