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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Blake62 on October 13, 2008, at 3:42:17
Hey, all.
I've been on 150 mgs. of Zoloft (and 1 mg. of Klonipin) for several weeks now for depression and social anxiety. Every time I go up on the Zoloft, I feel better for about a week, then it starts to poop out. I know this is all pretty much a crapshoot, but has anyone had success augmenting Zoloft with other meds, or would anyone have any suggestions about what to try? Many, many thanks.
Posted by mav27 on October 13, 2008, at 4:17:35
In reply to Drugs to augment Zoloft: Any suggestions?, posted by Blake62 on October 13, 2008, at 3:42:17
Lithium and low dose atypical anti-psychotics would be the usual things to use.
Posted by azalea on October 13, 2008, at 7:47:59
In reply to Drugs to augment Zoloft: Any suggestions?, posted by Blake62 on October 13, 2008, at 3:42:17
There are many options for augmenting SSRIs like Zoloft. Wellbutrin is an option, although probably not the best choice if you also have anxiety as it can increase anxiety in some people. Another option would be a mood stabilizer such as Lamictal or Lithium. When you say "poop out," which symptoms are returning?
Other options include buspirone, pindolol, and atypical antipsychotics.
> Hey, all.
> I've been on 150 mgs. of Zoloft (and 1 mg. of Klonipin) for several weeks now for depression and social anxiety. Every time I go up on the Zoloft, I feel better for about a week, then it starts to poop out. I know this is all pretty much a crapshoot, but has anyone had success augmenting Zoloft with other meds, or would anyone have any suggestions about what to try? Many, many thanks.
Posted by Blake62 on October 13, 2008, at 17:50:34
In reply to SSRI augmentation » Blake62, posted by azalea on October 13, 2008, at 7:47:59
> There are many options for augmenting SSRIs like Zoloft. Wellbutrin is an option, although probably not the best choice if you also have anxiety as it can increase anxiety in some people. Another option would be a mood stabilizer such as Lamictal or Lithium. When you say "poop out," which symptoms are returning?
>
> Other options include buspirone, pindolol, and atypical antipsychotics.
>
> > Hey, all.
> > I've been on 150 mgs. of Zoloft (and 1 mg. of Klonipin) for several weeks now for depression and social anxiety. Every time I go up on the Zoloft, I feel better for about a week, then it starts to poop out. I know this is all pretty much a crapshoot, but has anyone had success augmenting Zoloft with other meds, or would anyone have any suggestions about what to try? Many, many thanks.
>
> Thanks. When I say the symptoms return after pooping out, I mean both the depression (primarily), and the anxiety both. I don't think the Zoloft has done much for the anxiety; I think it's primarily the depression it helps. A few meds other people have mentioned to try as augmentation agents are Strattera, Memantine, Pamelor, and Provigil.
Posted by azalea on October 13, 2008, at 19:32:52
In reply to Re: SSRI augmentation, posted by Blake62 on October 13, 2008, at 17:50:34
Augmenting Zoloft with Straterra might be a good option. Straterra is FDA-approved for ADHD, but was originally developed as an antidepressant. It inhibits norepinephrine reuptake, which would work well in combination with Zoloft which inhibits serotonin reuptake. Another option would be switching to a dual reuptake inhibitor such as Effexor, Cymbalta, or Pristiq. These medications inhibit reuptake of both serotonin and norepinephrine.
> > There are many options for augmenting SSRIs like Zoloft. Wellbutrin is an option, although probably not the best choice if you also have anxiety as it can increase anxiety in some people. Another option would be a mood stabilizer such as Lamictal or Lithium. When you say "poop out," which symptoms are returning?
> >
> > Other options include buspirone, pindolol, and atypical antipsychotics.
> >
> > > Hey, all.
> > > I've been on 150 mgs. of Zoloft (and 1 mg. of Klonipin) for several weeks now for depression and social anxiety. Every time I go up on the Zoloft, I feel better for about a week, then it starts to poop out. I know this is all pretty much a crapshoot, but has anyone had success augmenting Zoloft with other meds, or would anyone have any suggestions about what to try? Many, many thanks.
> >
> > Thanks. When I say the symptoms return after pooping out, I mean both the depression (primarily), and the anxiety both. I don't think the Zoloft has done much for the anxiety; I think it's primarily the depression it helps. A few meds other people have mentioned to try as augmentation agents are Strattera, Memantine, Pamelor, and Provigil.
>
>
Posted by cactus on October 16, 2008, at 6:54:26
In reply to Re: SSRI augmentation » Blake62, posted by azalea on October 13, 2008, at 19:32:52
I'd try modafinil first if you're not suffering from anxiety, or maybe a DA. I found the Dopamine Agonist ropinirole (requip/repreve) and zoloft was a great combo. I don't tolerate SSRI's very well at all, but when ropinirole was added it made things much better, I stopped the zoloft which was horrendous for me personally and continued on with the ropinirole. Once the zoloft withdrawal was over I did much better on the ropinirole alone. It just got too expensive though and it can have some side effects, so I switched to modafinil which is slightly cheaper where I live, it works even better and I virtually have no side effects from it at all.
I never took zoloft and modafinil at the same time though, Peace C
Posted by bulldog2 on October 16, 2008, at 16:34:46
In reply to Drugs to augment Zoloft: Any suggestions?, posted by Blake62 on October 13, 2008, at 3:42:17
> Hey, all.
> I've been on 150 mgs. of Zoloft (and 1 mg. of Klonipin) for several weeks now for depression and social anxiety. Every time I go up on the Zoloft, I feel better for about a week, then it starts to poop out. I know this is all pretty much a crapshoot, but has anyone had success augmenting Zoloft with other meds, or would anyone have any suggestions about what to try? Many, many thanks.deplin
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