![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by jonh kimble on October 26, 2007, at 4:05:54
hi, after a couple years I am back. Hope you're all well, but I guess you wouldn't be if you are still here.
Anyway, I am on Nardil 90 mg a day, Zyprexa 10 mg a day, and Ativan 2 mg a day. I also have a prescription for dextroamphetamine 40 mg a day and I am taking the Dexedrine together with the Nardil although I just started Nardil, and maybe my levels of MAO are not very much inhibited yet. I'm wondering how safe it is to combine the two. Also, I've taken Nardil before at 90 mg and didn't find it did very much, but I think I'm already feeling it on less than one week. Could the Zyprexa be potentiated it? Like how Prozac and Zyprexa are synergistic. Also, last time I took Nardil, I only stayed on 90 mg for about three weeks. How long can it take for it to kick in? And just in case you're wondering, I'm taking it for atypical depression and social phobia, and all that that entails.
Thanks for your responses,
Thomas Roe
Posted by King of Nothing on October 26, 2007, at 10:12:02
In reply to Nardil questions, posted by jonh kimble on October 26, 2007, at 4:05:54
> hi, after a couple years I am back. Hope you're all well, but I guess you wouldn't be if you are still here.
>
> Anyway, I am on Nardil 90 mg a day, Zyprexa 10 mg a day, and Ativan 2 mg a day. I also have a prescription for dextroamphetamine 40 mg a day and I am taking the Dexedrine together with the Nardil although I just started Nardil, and maybe my levels of MAO are not very much inhibited yet. I'm wondering how safe it is to combine the two. Also, I've taken Nardil before at 90 mg and didn't find it did very much, but I think I'm already feeling it on less than one week. Could the Zyprexa be potentiated it? Like how Prozac and Zyprexa are synergistic. Also, last time I took Nardil, I only stayed on 90 mg for about three weeks. How long can it take for it to kick in? And just in case you're wondering, I'm taking it for atypical depression and social phobia, and all that that entails.
>
> Thanks for your responses,
> Thomas RoeI've heard/read 4-6 weeks. But, it's very individual..could be one week for you, or as long as 6-8 wks.
Posted by mav27 on October 26, 2007, at 11:02:14
In reply to Re: Nardil questions, posted by King of Nothing on October 26, 2007, at 10:12:02
Took exactly 3 weeks and 1 day for it to kick in for me, was like a switch was flicked in my brain one night. A bunch of side effects also kicked in that night as well though.
Posted by Justherself54 on October 26, 2007, at 12:08:29
In reply to Nardil questions, posted by jonh kimble on October 26, 2007, at 4:05:54
Hope I'm not hijacking the thread! I'll be starting Nardil in a few days cause parnate caused me to have terrible chills..but I have to sit and stare at my prescription for awhile before I fill it cause starting a new med always scares the you know what out of me..I'm expecting some of the same side effects as Parnate..but are there some different ones I can expect?
One thing..Parnate gave me incredible motivation, focus and concentration at home but I still was terribly uncomfortable with social interactions..can I expect the same from Nardil? I'm kinda hoping it'll be better for me socially..I'm terrible for isolating myself at the best of times..any comments greatly appreciated!
Posted by cumulative on October 26, 2007, at 15:20:25
In reply to Nardil questions, posted by jonh kimble on October 26, 2007, at 4:05:54
>I also have a prescription for dextroamphetamine 40 mg a day and I am taking the Dexedrine together with the Nardil although I just started Nardil, and maybe my levels of MAO are not very much inhibited yet.
That's not very safe at all. I'm very much in favor of careful stimulant-MAOI combinations, but you need to titrate upwards from a very small dose, like 5mg. There's someone here who had a hypertensive reaction at 10mg dexedrine with Nardil, IIRC.
Posted by Sigismund on October 26, 2007, at 17:08:43
In reply to Re: Nardil questions, posted by cumulative on October 26, 2007, at 15:20:25
>but you need to titrate upwards from a very small dose, like 5mg.
Or maybe 2.5mg?
Posted by stargazer2 on October 26, 2007, at 21:13:18
In reply to Re: Nardil questions, posted by Sigismund on October 26, 2007, at 17:08:43
to nardil and amphetamine salts at 10 mg. 5 mg was fine. Be careful with any amphetamines and Nardil, making sure your pdoc is an expert and that you have a medication to counteract a hypertensive reaction should you have one. I was lucky in that I didn't have to go to the hospital and had Nifedipine and a BP cuff and was able to monitor my BP (went to 230/130)as it slowly declined after taking 10 mg of Nifedipine.
Stargazer
Posted by Ron Hill on October 27, 2007, at 23:20:38
In reply to Nardil questions, posted by jonh kimble on October 26, 2007, at 4:05:54
Thomas> Anyway, I am on Nardil 90 mg a day, Zyprexa 10 mg a day, and Ativan 2 mg a day. I also have a prescription for dextroamphetamine 40 mg a day and I am taking the Dexedrine together with the Nardil although I just started Nardil, and maybe my levels of MAO are not very much inhibited yet. I'm wondering how safe it is to combine the two.
40 mg/day of dex added to 90 mg/day of Nardil is a hypertensive crisis waiting to happen. Did your p-doc rx the 40 dex along with the 90 Nardil? If so, what is your p-doc thinking?
Like posters above have said, a low dosage of a pstim can often be carefully added to Nardil without problems. However, you have to start out taking micro doses, and increase very very slowly while keeping a very close watch on your blood pressure.
Please be very careful with this, and do not treat the risk lightly.
Rule Number One: Nobody gets hurt.
Rule Number Two: Do not forget Rule Number One!Nice to see you back, Thomas.
-- Ron
Bipolar II with ultra rapid cycling (15 day cycle), and mild Obsessive Compulsive Personality Disorder (OCPD)
600 mg/day Trileptal
200 mg/day Lamictal
875 mg/day Keppra
90 mg/day Nardil
15 mg/day Deplin
Thomas Roe
Posted by Questionmark on November 6, 2007, at 0:56:23
In reply to Nardil questions, posted by jonh kimble on October 26, 2007, at 4:05:54
Welcome back. I've only been recently sporadically back as well.
I agree with everything the others said. 40mg dextroamphetamine *might* be ok with the Nardil, but you should definitely not start out that high. I would agree that 2.5 or MAYbe 5mg would be appropriate to start out, and slowly increase.
And it certainly is possible to feel Nardil in less than one week. Keep in mind that if you feel a case of even worse depression creep up within that first month (after feeling the "Nardil response"), it will pass shortly (after few days or so). It's only your receptors adapting. You might not have that at all though.
I have atypical (at least mostly atypical) depression and SP as well, along with some other crap. I don't know how you can handle Zyprexa. I think that would be a straight immobile zombie drug for me (judging from other APs and the fact that its highly antihistaminic).
You dont have to answer that was mostly rhetorical.
Anyway good luck to you.
> hi, after a couple years I am back. Hope you're all well, but I guess you wouldn't be if you are still here.
>
> Anyway, I am on Nardil 90 mg a day, Zyprexa 10 mg a day, and Ativan 2 mg a day. I also have a prescription for dextroamphetamine 40 mg a day and I am taking the Dexedrine together with the Nardil although I just started Nardil, and maybe my levels of MAO are not very much inhibited yet. I'm wondering how safe it is to combine the two. Also, I've taken Nardil before at 90 mg and didn't find it did very much, but I think I'm already feeling it on less than one week. Could the Zyprexa be potentiated it? Like how Prozac and Zyprexa are synergistic. Also, last time I took Nardil, I only stayed on 90 mg for about three weeks. How long can it take for it to kick in? And just in case you're wondering, I'm taking it for atypical depression and social phobia, and all that that entails.
>
> Thanks for your responses,
> Thomas Roe
Posted by Questionmark on November 6, 2007, at 1:01:35
In reply to Re: Nardil questions, posted by Justherself54 on October 26, 2007, at 12:08:29
Hi. You probably should have started a new thread for this, but no big deal. I have experience with Parnate and Nardil.
Pretty much, from my experience, Nardil will essentially be the opposite of your Parnate descriptions. Nardil is miraculously magical for socializing. But it -- it can-- make you somewhat less motivated and able to concentrate. But it is The Antidepressant Drug, if there is any.
> Hope I'm not hijacking the thread! I'll be starting Nardil in a few days cause parnate caused me to have terrible chills..but I have to sit and stare at my prescription for awhile before I fill it cause starting a new med always scares the you know what out of me..I'm expecting some of the same side effects as Parnate..but are there some different ones I can expect?
>
> One thing..Parnate gave me incredible motivation, focus and concentration at home but I still was terribly uncomfortable with social interactions..can I expect the same from Nardil? I'm kinda hoping it'll be better for me socially..I'm terrible for isolating myself at the best of times..any comments greatly appreciated!
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.