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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by Dragoon on October 25, 2006, at 0:08:35
Has anyone had a personal expereince with the usage of Seroquel and Provigil combined?
Im currently taking 25mg seroquel for sleep and it has caused some somnolence. Ive read extensively on both compunds and have yet to see any interactions in literature.
Has anyone had any ancedotal expereinces with these two?
Posted by Lindenblüte on October 25, 2006, at 8:31:04
In reply to Modafinil(Provigil)Quetiapine(Seroquel)Interaction, posted by Dragoon on October 25, 2006, at 0:08:35
> Has anyone had a personal expereince with the usage of Seroquel and Provigil combined?
>
> Im currently taking 25mg seroquel for sleep and it has caused some somnolence. Ive read extensively on both compunds and have yet to see any interactions in literature.
>
> Has anyone had any ancedotal expereinces with these two?
Hey! I took 25mg seroquel + 60 mg cymbalta for a couple of weeks, and the sleepiness became better over time. Then I went up to 90mg cymbalta, and the sleepiness persisted after a month.I added 200mg provigil, and that combination 25mg seroquel + 90mg cym + 200mg provigil pulled me right out of a bad depression. Felt productive, had a really nice summer (lots of international travel, so it was nice to have a sleepy med and a wakey med).
More recently I have been taking 300mg seroquel, and I've had THE HARDEST time waking up for a couple weeks (starting to get better). I think the only thing that saved me from being a complete zombie was that I could manage to put my provigil and a glass of water next to bed every night, and when the alarm rang, I could barely slurp it down, hit snooze half dozen times. Then like magic-- at some point after 30-45 mins of hitting snooze, I'd feel like I could actually open my eyes- felt a little awake- enough to make coffee and then I would be all better.
I take my seroquel at the same time every night (as babble-chatters can attest to!) and then try my hardest to stay out of bed for 30 mins, until I totally CRASH.
Keeping a regular schedule helps. Give it 2 weeks before you think that you need provigil. It's kind of expensive.
-Li
Posted by Dragoon on October 25, 2006, at 9:10:52
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac » Dragoon, posted by Lindenblüte on October 25, 2006, at 8:31:04
Thanks alot linden! I already took 50mg of Modafinil today and we'll see how that goes. I have taken 100mg for 4-5 days in the past without seroquel and did pretty well untill i stopped it and began to show symptoms of psychosis. I know its expensive and i dont even have a prescription for it (the doctor just would plain not give it to me). I got it from a very legit place though and at a fairly decent price. He gave me straterra as apposed to Modafy for the risk of manic swing. I try to tell him the litarature but he really didnt know what he was talking about when it came to the drug. Strattera has just as much instances or probably more of mania and psychosis. To sum it up though, you can only look at ancetodal eveidence on Modafinil with antipsychotics to find out there effects at the moment. Theres been one pretty long study with schizophrenics but i mean they're already on crazy doses of everything.Studies will bloom soon though because theres alot of tests going on with using it as an adjunct to SSRIs and antipsychotics (they're just not done yet).
Has anyone else has expereinces with the two?
Posted by Lindenblüte on October 25, 2006, at 10:12:01
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac, posted by Dragoon on October 25, 2006, at 9:10:52
you're most welcome, Dragoon.
I'm taking 300mg seroquel not for psychosis (I'm not psychotic) but mainly for intrusive thoughts and flashbacks related to earlier chronic trauma.
Seroquel is getting quite the buzz on the boards lately becuase it's now approved to treat bipolar mania, bipolar depression, as well as psychosis.
I'm trying not to think of myself as a crazy cuckoo, which someone might automatically assume, when finding out that I'm taking hundreds of mg of seroquel, an "antipsychotic"
I prefer to think of myself as
Her Royal Highness, Princess of Polypsychopharmacy, Lindenblüte.I hope that the modafinil does the trick for you. It's supposed to be especially good stimulant because it doesn't disrupt sleep as much as the amphetamine-type stimulants. I certainly find that it has far fewer of the jittery heart-palpitation type feelings than when I took diet pills or ephedra (back in the day!)
maybe time to find a new pdoc, or perhaps you need to tell your GP that you suffer from sleep apnea or narcolepsy or something like that.
H.R.H. PoPpp, Li
Posted by dbc on October 25, 2006, at 12:00:29
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac » Dragoon, posted by Lindenblüte on October 25, 2006, at 10:12:01
I realize you were probably joking but faking narcolepsy is a very bad idea. That will get you labeled "drug seeker" faster than anything. Well..aside from going in and saying "i have ADD". My doctor literally gets 3 people every single day that magically have come down with adhd.
Posted by Lindenblüte on October 25, 2006, at 12:13:04
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac, posted by dbc on October 25, 2006, at 12:00:29
> I realize you were probably joking but faking narcolepsy is a very bad idea. That will get you labeled "drug seeker" faster than anything. Well..aside from going in and saying "i have ADD". My doctor literally gets 3 people every single day that magically have come down with adhd.
Oh. good point. Well, as it turns out, my mom has both sleep apnea AND narcolepsy, but it never even occurred to her to ask for a stimulant until a relative was prescribed modafinil for cancer-related fatigue. Her GP didn't ask any questions, wrote a Rx on the spot.
I feel like (duh). I'm sorry- I was being thoughtless, and you're right. One shouldn't lie to a MD about symptoms only to get a prescription. I'm just thinking that it might be better to work with a new pdoc, rather than get one's (Rx) meds without a prescription, no matter how legitimate the source.
-Li
Posted by Phillipa on October 25, 2006, at 13:06:44
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac » Dragoon, posted by Lindenblüte on October 25, 2006, at 8:31:04
Expensive? My pdoc thought if an ad didn't work this time she might add it. How expensive is expensive with no insurance? Love Phillipa
Posted by dbc on October 25, 2006, at 13:56:39
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac » Lindenblüte, posted by Phillipa on October 25, 2006, at 13:06:44
http://www.walgreens.com/library/finddrug/druginfo1.jsp?particularDrug=Provigil&id=15151
Yeah...this is why i never tried it.
Posted by Lindenblüte on October 25, 2006, at 16:17:35
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac, posted by dbc on October 25, 2006, at 13:56:39
Hmm, so it costs me about 10 a day plus coffee and tea to keep me up?
wow. I'm not sure that my wakefulness is so important to society. I feel guilty.
I'm expensive. Somebody somewhere is paying for me, because my copay is only about enough to buy one tablet.
I feel profound guilt. maybe I should just sleep.
-Li
Posted by Dragoon on October 25, 2006, at 18:56:03
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac » dbc, posted by Lindenblüte on October 25, 2006, at 16:17:35
Hah im going to pretend im narcoleptic next time i see the doctor. Im just going to walk in the office and fall flat on my face. This should get me some drugs REAL quick, or maybe a psyche ward visit...I got my Modafinil illegaly i guess you can say from a legetiment overseas seller. It took about 2 weeks to get here but its the real stuff.
I feel good right now.;at first i had very rapid cycling for the first 3 hours of the day which was very unsettling, but it evened out and im cool and cognitive now. Tomorow im going to take 100mgs and probably stick to that dose. The anxiety from it can be unbearable at times and i need to find a adjunct for it. I was looking along the lines of Holy basil,this magnesium/taurine combo i have, and maybe phosphtydlecholine. I already take high dose fish oil (5-10grams aday) and i dont know how id feel without that. REAL R-Lipoic acid seems to help as well. Theres a study i cant seem to find that indicates that modafinil minorly enhances cortisol and its dose dependent.Anyways we'll see how it goes i guess. Im going to the bar with some freinds now and plan to only have 2 drinks. Its not the smartest but i think ill survive tonight.
Dont feel bad Lindenblüte. The only reason its so high is because its in a specialized class, and theres just no reason to charge that much for it in the first place. I mean seriously i got 50 200mgs tablets of generic modafy for $65 plus shipping. I dont feel bad at all
Posted by Lindenblüte on October 25, 2006, at 21:34:08
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac, posted by Dragoon on October 25, 2006, at 18:56:03
Okay,
well, as long as I know that insurance money is going to support the pharma companies as they do very important research on drugs for dying, or at least cosmetically sufferring people.-Li
Posted by Dragoon on October 26, 2006, at 2:01:50
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac » Dragoon, posted by Lindenblüte on October 25, 2006, at 21:34:08
Your absolutely correct Linden. And honestly i havent read enough into the health care system to elaborate on the matter;thats on my to do list. I beleive it is true though that the health care system is kind of whack and we do pay way too much for ESSENTIAL precriptions.I'm doing this because i feel that is is essential for my situation ..and if i had a prescription i would gladly give them money...
Posted by Gabbi~G on October 26, 2006, at 18:44:26
In reply to Re: Modafinil(Provigil)Quetiapine(Seroquel)Interac » Dragoon, posted by Lindenblüte on October 25, 2006, at 8:31:04
My experience with the two has been positive.
I don't take much seroquel, but when I do sometimes It will leave me a zombie til 3 in the afternoon.
The provigil, well I love provigil, it's almost too good to be true for me, but it lifts the sleepiness, and I feel very together, productive, and I can put things that would previously have spiralled me into a deep depresssion, into perspective, without feeling anxious or "high" meaning, I can still feel sad, but I'm experience sadness, in proportion the situation.
So that's what I have to say. : )
This is the end of the thread.
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