Shown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by adamCanada on October 24, 2006, at 0:42:28
I am currently on paxil and I need something to take along with it to help with my clinical depression. Paxil has helped me a lot but there is still a long way to go. I also have huge social anxiety which paxil has helped a lot with as well. I also have strong insomnia.
Some meds which have been recommended to me recently by one of the best doctors I have yet to meet are...
Remeron, Modafinil, Risperidal, pramipexole, and desipramine.
Modafinil I put in there because I once tried adrafinil and while in the long run it backfired it did make me feel great for one day.
I have several problems and finding out the pros and cons of such meds could help me make my decision on what to try next. I have gone through 15+ meds with little relief.
Risperidal helped me a bit before when I took it by itself. Maybe with paxil it will be a good combination.
Aside from huge lack of interest or motivation to do anything my other symptoms include:
DULLNESS (I feel like an idiot often, I used to be so brilliant before this accutane induced depression hit)
Poor memory
VERY LOW sex drive (remeron seems great for this)
Low appetite
Insomnia
What can help restore mental capability? Other problems helped would be welcome as well.Need any advice you guys are willing to share
Posted by Declan on October 24, 2006, at 3:28:15
In reply to Which meds restore brain power?, posted by adamCanada on October 24, 2006, at 0:42:28
Adam, I don't think there's much at all on this board that will do what you want in this respect. There seems to be inevitable toxicity with many meds. You know this yourself with your experience with Accutane. In order to get what you want you need a holistic approach IMO, with a bare minimum of toxicity from those drugs that are essential to you, if you get my drift.
Posted by mike lynch on October 24, 2006, at 12:34:12
In reply to Re: Which meds restore brain power?, posted by Declan on October 24, 2006, at 3:28:15
try pircetam, dmae, they're alternative meds, but there are studies and they've helped many people. Just research them
Posted by Declan on October 24, 2006, at 14:14:05
In reply to Which meds restore brain power?, posted by adamCanada on October 24, 2006, at 0:42:28
Deprenyl, Hydergine, although perhaps not vinpocetine, may aggravate insomnia. Piracetam and that lot may aggravate depression. So it's how you work your way around that. In my opinion it is really important to have good restorative sleep, good nutrition and a minimum of toxicity.
Posted by Racer on October 24, 2006, at 14:18:17
In reply to Which meds restore brain power?, posted by adamCanada on October 24, 2006, at 0:42:28
I don't have an answer for you -- Paxil did the same thing to me, though, in terms of brain fog...
Out of the meds you listed, I'd suggest Provigil first. It's a fairly benign little drug, in my experience, it certainly boosted my mood for a long time -- even when it was the only thing I was taking -- and the only side effect I got from it was short lived. (I got headaches, but they weren't bad headaches -- just kinda like my skull was a bit tight. They weren't even enough to warrant taking an aspirin. And they went away quickly.) It's also likely to work right away, so you'd know in about a week if it was going to be a winner for you.
The others I don't know anything much about, so I can't comment.
Here's a question, though: Paxil is helping you, but causing this problem. Have you tried other SSRIs? Maybe one of them would help, but not cause this? (And, of course, I know it's likely you HAVE tried other SSRIs. Just thought I'd suggest what seemed obvious, just in case...)
Good luck to you, and do let us all know what you decide to do, and what the results are, 'K?
Posted by zeugma on October 25, 2006, at 18:14:59
In reply to Re: Which meds restore brain power?, posted by Declan on October 24, 2006, at 14:14:05
In my opinion it is really important to have good restorative sleep, good nutrition and a minimum of toxicity. >>
I agree, but what is the 'minimum' of toxicity? The smallest amount of toxicity needed to get a 'therapeutic' effect? This can be quite toxic.
My pdoc would love to have me on the fewest meds possible. Klonopin (1 mg) is not very toxic. Neither is buspirone (15 mg). But as doses ascend, so does toxicity, and the way stimulants and AD's are dosed, it's start at the least amount and hope for the best.
Since toxicity seems so dose-dependent, I read an article in which paroxetine was recommended as a way to slow down rapid metabolizers of nortriptyline, who need high doses to have an effect but experience the inevitable toxicity from all the metabolites floating around. The same logic would apply to desipramine (theoretically a low dose would be therapeutic with Paxil).
-z
Posted by Declan on October 26, 2006, at 23:09:46
In reply to Re: Which meds restore brain power? » Declan, posted by zeugma on October 25, 2006, at 18:14:59
Yeah, well that's it, hey Z. The minimum of toxicity is the least we can organise, which is no doubt more than enough. Tianeptine has a half life of 2 or 3 hours, and I wish I could make it longer. And though it's very well tolerated it's a bit toxic for me. After every dose I can notice a worsening of my sinus condition (very high IgE).
Posted by adamCanada on October 27, 2006, at 3:40:34
In reply to Re: Which meds restore brain power?, posted by Declan on October 26, 2006, at 23:09:46
> Yeah, well that's it, hey Z. The minimum of toxicity is the least we can organise, which is no doubt more than enough. Tianeptine has a half life of 2 or 3 hours, and I wish I could make it longer. And though it's very well tolerated it's a bit toxic for me. After every dose I can notice a worsening of my sinus condition (very high IgE).
Do you feel the Taineptine helps you in a very different way than SSRI's? I been on most SSRI's and the only one to help me much is Paxil.
How has taineptine been different for you than other AD's?
Posted by Declan on October 27, 2006, at 7:32:02
In reply to Re: Which meds restore brain power?, posted by adamCanada on October 27, 2006, at 3:40:34
My experience with ADs is very limited, due to unpleasant experiences with other psych drugs and lack of faith in such things generally. The ones I have tried are
Deprenyl
Parnate
Remeron
MoclobemideSo I have never tried an SSRI, and never will because my depression is not bad enough to make putting up with the s/e worthwhile. Anyway, I don't want to feel numb. That's why I've given up methadone.
However I have heard that the subjective effect of tianeptine is not so dissimilar to SSRIs, but with fewer side effects.
Deprenyl, Parnate and tianeptine are ADs I'd take. Bugger Remeron, though I have to say that it's a bit prosexual, at least while you're asleep. Dreadful once you wake up.
This is the end of the thread.
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