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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by Joe1 on April 14, 2005, at 0:19:35
Is there anyone out there that has tried Marplan
maoi . If so, how did it work for you.
thanks for any info you have.
Joe
Posted by willyee on April 16, 2005, at 8:05:38
In reply to New Nardil to Parnate to Marplan, posted by Joe1 on April 14, 2005, at 0:19:35
> Is there anyone out there that has tried Marplan
> maoi . If so, how did it work for you.
> thanks for any info you have.
> JoeMight be some that dont agree,but you can basicaly follow the trend of responses on various groups.
Parnate and Nardil are your heavy hitters,the ones you want to try first,hopefully one will work of the two,lucky people get relieaf from both,but they are the most powerful effective heavy hitters.If one can not get a hold of these,LIQUID deprenyl used with a BENZO or sedative (alone is way too stimulating) can be a possable third choice.
Molcamide is not spoke about with success to often cause well it isnt a successful one.It has a more direct stimulant come one,and once thats over thats it,sorta like caffiene,theres no rounded over all anti-deprassant mood lift that stays in the background getting u through the day like parnate/nardil.Its kinda like caffine its direct and boom,i think it might adjunct a med ok when fatigue is a problem,but used alone,i dont see it being a stable med at all.
Marplan,i just rember waiting weeks and weeks to finally achive a effect slightly,and i over emphasis SLIGHTLY similiar to the effect parnate/nardil provide almost initialy.
Parnate....nardil.....liquid deprenyl used with a med to control anxiety would be your primary options,and this is simply my own a opinion.
There are a few over seas Maois such as molcamide,and gerovital k3 i think is the name that get mentioned a lot but i think this is so more so out of curiosity since less people report on them,when they are reported on the information usualy isnt encoruaging.
From what i understand,unfrotaunlty not having myself,was the old formualtion of nardil,i believe unavalable now was the true gold standard,figures i want it and now its gone,sheeshzzzzzzzzzzz
Posted by ed_uk on April 16, 2005, at 14:54:40
In reply to Re: New Nardil to Parnate to Marplan, posted by willyee on April 16, 2005, at 8:05:38
Hello,
>Marplan,i just rember waiting weeks and weeks to finally achive a effect slightly,and i over emphasis SLIGHTLY similiar to the effect parnate/nardil provide almost initialy.
I think there's been a tendency to prescribe Marplan at inadequate doses. Some patients may need up to 80mg a day. Perhaps you should try it again at a higher dose!
Regards,
Ed.
Posted by willyee on April 16, 2005, at 22:24:04
In reply to Re: New Nardil to Parnate to Marplan » willyee, posted by ed_uk on April 16, 2005, at 14:54:40
> Hello,
>
> >Marplan,i just rember waiting weeks and weeks to finally achive a effect slightly,and i over emphasis SLIGHTLY similiar to the effect parnate/nardil provide almost initialy.
>
> I think there's been a tendency to prescribe Marplan at inadequate doses. Some patients may need up to 80mg a day. Perhaps you should try it again at a higher dose!
>
> Regards,
> Ed.
Im sure thats a possablility,but personaly the only med ill go back on is either a new formulated nardil where there is some kind of agreement but at least a small number of users that the med is as it was.Id also add liquid deprenyl in very small doses to cut back fatigue on parnate,i would not however swtich to the lesser maois simply because on remedyfind.com and various groups and boards there is not enough info to pursua their use as there is parnate and nardil,if your talking to the first poster than i guess anything is plausable since we are all so different and respons as such,either way good luck to the orginal poster,keep us informaed of any postive progress please!
Posted by Joe1 on April 17, 2005, at 23:45:41
In reply to Re: New Nardil to Parnate to Marplan, posted by willyee on April 16, 2005, at 22:24:04
Thanks for the info. I think I'll just stay on
the parnate since i know it helps . The old nardil
was the only thing that helped me. Then when they
changed to the new nardil - it completely failed in every way.I can't wait weeks to get a similar
effect to parnate.The parnate isn't as consistant
as the old nardil - some days it seems to work and
some days it's not there ? does that sound normal?
I think I'll skip the marplan .
Thank You
Joe
Posted by willyee on April 18, 2005, at 5:55:32
In reply to Re: New Nardil to Parnate to Marplan, posted by Joe1 on April 17, 2005, at 23:45:41
> Thanks for the info. I think I'll just stay on
> the parnate since i know it helps . The old nardil
> was the only thing that helped me. Then when they
> changed to the new nardil - it completely failed in every way.I can't wait weeks to get a similar
> effect to parnate.The parnate isn't as consistant
> as the old nardil - some days it seems to work and
> some days it's not there ? does that sound normal?
> I think I'll skip the marplan .
> Thank You
> Joe
>
My friend you just described parnate to a tee,it can be one of the most FRUSTARATING,ANNOYING,HELPFUL,LIFE SAVING MEDS OUT.Its a love hate relationship,if id knew of an alternative i dident already try id send it packing.
For now i just read close,try augment strategies,dosing strategies,sometimes it works great,sometimes i get myself in trouble,definatly not a way a med should work,but to the ney sayers,all i can say is i have gone 6 weeks on the med alone,as said to be taken,and that is not an option,for me the med needs to be constatnly tweaked,booh.
Posted by stargazer on April 18, 2005, at 22:41:54
In reply to Re: New Nardil to Parnate to Marplan, posted by willyee on April 18, 2005, at 5:55:32
I took all 3 of the MAO's many years ago, prior to Prozac being available.
Marplan was taken off the market while I was on it back in the early 1990's. Does anyone else remember this?
I wrote a letter to the manufacturor(Roche) at the time trying to plead my case to no avail. So I was tapered off of it and told that the other MAO's should work as well. They didn't and I went into a full blown relapse and stayed there for a good year and a half trying to find another drug that would help me function again.
I just lost track of it (Marplan)never hearing anything about it again but now hearing its available, wondering if it would work for me again. Perhaps I'll let my Pdoc know about it's availability. Does anyone know when it was rereleased?
I've been relatively stable for awhile now, but I would certainly try it again if necessary, although, the dietary restrictions were always a problem. I just would like to take one pill or two a day rather than the five I am now taking.
One pill a day is almost normal, taking five indicates I'm sick, dependent on the pills to keep me alive and functioning. There's alot more responsibility that goes into scheduling when to take each pill, making sure you have enough, getting approval for the Adderall, paying for them.
And there are still people that think depression is something you bring on yourself or use as an excuse for why you can't do things like everyone else. Yeah, like I would wish my life on my worse enemy. It may normal to the untrained eye but underneath it all there's alot of pain and struggle getting through some days.
Any info on the NEW Marplan would be appreciated. Both good and Bad feedback.
Posted by katy2 on April 24, 2005, at 10:57:13
In reply to Re: New Nardil to Parnate to Marplan, posted by willyee on April 16, 2005, at 8:05:38
I have been on Marplan since the early 80's and can tell you it has saved my life. I have tried others but nothing else works. When Roche stopped producing Marplan my doc talked me into trying something different. I promptly went into a horrible summer of depression and was desperate to get back on Marplan. I've learned to live with the restrictions- they seem minimul when compared to the alternative days of depression- Marplan is still available...at least I think it is though my pharmacist seems to be having trouble getting ahold of more right now and I'm not sure why. Here is the link from the press release when Oxford Pharmaceutical took over the manufacture of Marplan from Roche -http://www.oxfordpharm.com/Press%20Release.htm
Oxford Pharmaceutical Services Questions to Dr. Richard Guarino at 973-256-0600 or guarino@oxfordpharm.com
I sure hope there are no problems getting my refill tomorrow- but just in case tell me- you say you have had good luck with Prozac? I tried Wellbutrin and no go.
Posted by stargazer on April 25, 2005, at 20:57:03
In reply to Re: New Nardil to Parnate to Marplan, posted by katy2 on April 24, 2005, at 10:57:13
Katy,
Have you been on Marplan since it was discontinued? I wasn't sure since you mentioned possibly having trouble getting the prescription refilled.
I on now on Celexa 40, Wellbutrin SR 150, Adderall XL 30, and now just put on Geodon 20 BID. I have had ups and downs over the past 10 years, some good years, some bad, related to my depression.
My current cocktail is much more complicated than Marplan alone was. But after not being on it since 1994 it would be very difficult to change my meds now.
But if I relapse again, which as you probably know is almost a given with this disease, I will look into taking it again.
The dietary restrictions are not that big of a hassle when you have your mind back.
Thanks for the press release. I have saved it for future reference.
When I read your post I thought I was reading one I had written, it sounded so familiar.
Posted by katy2 on April 26, 2005, at 16:53:33
In reply to Re: New Nardil to Parnate to Marplan. » katy2, posted by stargazer on April 25, 2005, at 20:57:03
Yes I have been on Marplan consistently, except for that one summer after Roche stopped making it and I tried some other drugs. I was so miserable I went back to Marplan - and I will tell you that I have been stable, quite happy and have had no relapses (except when I was not taking it-) Whatever it is that is missing in my chemical makeup- Marplan seems to takes care of it. It would be great to find something else that worked. I wonder if anyone else has found something that works as well as Marplan.
I have not even heard of some of what you are taking now- it sounds like a lot- but if it works that's what matters. Thanks for posting back.
katy
This is the end of the thread.
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