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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 19 of 19. This is the beginning of the thread.
Posted by Mel on January 4, 1999, at 19:33:24
I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
Posted by Elizabeth on January 5, 1999, at 1:07:36
In reply to SSRI induced mania?, posted by Mel on January 4, 1999, at 19:33:24
> I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
Uh, both - it's weird, but it occasionally happens. :-)
I had it on Paxil (not Zoloft, possibly Prozac) and
Effexor. (The Effexor actually caused a full-blown
mania - whee.) I'm not bipolar, BTW. There isn't
much information out there on this but from what I
can tell it is much more common in bipolar folks.
It's less common with Wellbutrin and MAOIs, supposedly.
Posted by Shelley on January 5, 1999, at 18:59:44
In reply to SSRI induced mania?, posted by Mel on January 4, 1999, at 19:33:24
> I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
Hi Mel!! This happened to me, too. Zoloft and Prozac were the easiest to tolerate. Effexor and Serzone were the worst. I don't know how common this is. I've never had a manic episode without the "help" of an SSRI. Thanks for bringing it up. I'm glad I'm not the only one and am glad to hear others experiences. Thanks for the buzz on Celaxa. I've been wary of trying it for this particular reason. Shell
Posted by Nancy on January 5, 1999, at 23:00:28
In reply to Re: SSRI induced mania?, posted by Shelley on January 5, 1999, at 18:59:44
> > I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
> Hi Mel!! This happened to me, too. Zoloft and Prozac were the easiest to tolerate. Effexor and Serzone were the worst. I don't know how common this is. I've never had a manic episode without the "help" of an SSRI. Thanks for bringing it up. I'm glad I'm not the only one and am glad to hear others experiences. Thanks for the buzz on Celaxa. I've been wary of trying it for this particular reason. ShellHi. Me too guys. SSRIs have sent me into full-blown psychotic manias!!! Talk about trippy. whoa!
I've ended up in restraints in psych wards for days at a time while on my SSRI flight! I'm a certifiable lunatic! Although, I do have moments of lucid clarity. Not very often but, I am blessed with them now and then.
Posted by Mel on January 6, 1999, at 15:54:08
In reply to SSRI induced mania?, posted by Mel on January 4, 1999, at 19:33:24
I'm not diagnosed as bipolar either, but have suspected for a few years that I may be. Some info I have found states that some people with *rapid* responses to AD's with subsequent loss of efficacy may actually be bipolar with the depression being the strong pole. I am printing out this info for my next dr. visit on the 26th. There is a Bipolar III diagnosis that is a "medicated into mania" type of bipolar disorder. I am fortunate that mine seems to be hypomania - no *dangerous* activity. Just overly energetic. (I jump up and down in place, do laundry at 1am, can't sleep, clean every nook and cranny, can't focus on reading one thing - I lose my attention span, etc.)
Thanks for replying to my post. I really appreciate it. ~Mel
Posted by Sean on January 6, 1999, at 17:57:00
In reply to SSRI induced mania?, posted by Mel on January 4, 1999, at 19:33:24
> I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
My story is the same; Zoloft put me on the moon. I
enjoyed it, but I always had to stop taking it
after a week. Then after a night or two of sleep,
boom, demon depression was back. How on earth can
a drug which causes insomnia be good for people
with tendencies towards bipolarity?
Posted by Shelley on January 6, 1999, at 23:17:26
In reply to Re: SSRI induced mania? and psychosis!, posted by Nancy on January 5, 1999, at 23:00:28
> > > I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
> > Hi Mel!! This happened to me, too. Zoloft and Prozac were the easiest to tolerate. Effexor and Serzone were the worst. I don't know how common this is. I've never had a manic episode without the "help" of an SSRI. Thanks for bringing it up. I'm glad I'm not the only one and am glad to hear others experiences. Thanks for the buzz on Celaxa. I've been wary of trying it for this particular reason. Shell
> Hi. Me too guys. SSRIs have sent me into full-blown psychotic manias!!! Talk about trippy. whoa!
> I've ended up in restraints in psych wards for days at a time while on my SSRI flight! I'm a certifiable lunatic! Although, I do have moments of lucid clarity. Not very often but, I am blessed with them now and then.
Me, too. I was just shy about mentioning the psychosis part of it. I didn't want to scare anybody who hasn't been through it. I'll never forget!!! Glad to see you're hear not there, Nancy!
Posted by Mel on January 7, 1999, at 15:04:46
In reply to SSRI induced mania?, posted by Mel on January 4, 1999, at 19:33:24
...a non-SSRI anti-depressant with non-psychotic results? Or is the SSRI with a mood stabalizer a better option? I have yet to try Welbutrin. What's everyone's take on that one? I hear one of the side effects is weight loss :) and another is increased sex drive :) (definitely a blessing to those of us who have been on these "anti-libido" meds) ~Mel
Posted by Elizabeth on January 8, 1999, at 14:22:26
In reply to anyone tried..., posted by Mel on January 7, 1999, at 15:04:46
> ...a non-SSRI anti-depressant with non-psychotic results? Or is the SSRI with a mood stabalizer a better option? I have yet to try Welbutrin. What's everyone's take on that one? I hear one of the side effects is weight loss :) and another is increased sex drive :) (definitely a blessing to those of us who have been on these "anti-libido" meds) ~Mel
I take Parnate and haven't had any mania problems with it. I don't require a mood stabilizer, apparently; it's only certain meds that cause me to "switch."
Wellbutrin made me really anxious (I have panic disorder as well as depression BTW), and I didn't tolerate TCAs (which may actually be even *worse* than SSRIs for causing manic reactions in susceptible folks). However, WB is supposed to be the best AD to try for bipolars who need an AD because it seems to cause fewer and milder manic/hypomanic reactions than other ADs do.
Posted by Nancy on January 8, 1999, at 16:34:13
In reply to Re: SSRI induced mania? and psychosis!, posted by Shelley on January 6, 1999, at 23:17:26
> > > > I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
> > > Hi Mel!! This happened to me, too. Zoloft and Prozac were the easiest to tolerate. Effexor and Serzone were the worst. I don't know how common this is. I've never had a manic episode without the "help" of an SSRI. Thanks for bringing it up. I'm glad I'm not the only one and am glad to hear others experiences. Thanks for the buzz on Celaxa. I've been wary of trying it for this particular reason. Shell
> > Hi. Me too guys. SSRIs have sent me into full-blown psychotic manias!!! Talk about trippy. whoa!
> > I've ended up in restraints in psych wards for days at a time while on my SSRI flight! I'm a certifiable lunatic! Although, I do have moments of lucid clarity. Not very often but, I am blessed with them now and then.
> Me, too. I was just shy about mentioning the psychosis part of it. I didn't want to scare anybody who hasn't been through it. I'll never forget!!! Glad to see you're hear not there, Nancy!
Guess we're just the lucky few on the lunatic fringe. ha ha. Psychosis is cool for a little while. Everything is like Disney Land, you know what I mean? Everything appears, well, UNUSUAL. And being Bipolar the voices that I hear say funny things, yea, like jokes and stuff. They can be coming from my clock radio (that's turned off) or from underneath my bed. We just chit-chat and giggle. Sometimes I hear music or chiors. Beautiful stuff. Oh, I could go on there's a lot of nifty stuff that goes along with being Bipolar psychotic (either while depressed or manic)!
Remember, WE'RE NEVER ALONE...hee hee. I thought you had the experience to appreciate that.
From the lunatic fringe,
Nancy
Posted by Nancy on January 8, 1999, at 16:49:14
In reply to anyone tried..., posted by Mel on January 7, 1999, at 15:04:46
> ...a non-SSRI anti-depressant with non-psychotic results? Or is the SSRI with a mood stabalizer a better option? I have yet to try Welbutrin. What's everyone's take on that one? I hear one of the side effects is weight loss :) and another is increased sex drive :) (definitely a blessing to those of us who have been on these "anti-libido" meds) ~Mel
Although I'm on the SSRI, Celexa, I'm also on Wellbutrin. Unfortunately, I can't give you info as to wether I like it or not. Because, I'm a treatment resistive Bipolar who is going to get ECT treatments in a couple of weeks. But, I CAN tell you that I don't experience any side effects. I hope that helps even a wee bit.
Nancy
Posted by Tess on January 9, 1999, at 7:26:56
In reply to Re: anyone tried...yes, posted by Nancy on January 8, 1999, at 16:49:14
I respond well to AD's but the side effects are ghastly. On Zoloft I became a slug, feeling like I was in a cloud or spacey much of the time, very tranquil. Because of the extreme muscle and joint pain I switched to Celexa and the cloud is lifted. In its place is what I would call hypomania. I can clean my entire house, shovel snow, reformat my hard drive, go for a 3 mile run, etc. all in one day. One extreme to the other, both places suck. Hoping for some balance someday.
> ...a non-SSRI anti-depressant with non-psychotic results? Or is the SSRI with a mood stabalizer a better option? I have yet to try Welbutrin. What's everyone's take on that one? I hear one of the side effects is weight loss :) and another is increased sex drive :) (definitely a blessing to those of us who have been on these "anti-libido" meds) ~Mel
> Although I'm on the SSRI, Celexa, I'm also on Wellbutrin. Unfortunately, I can't give you info as to wether I like it or not. Because, I'm a treatment resistive Bipolar who is going to get ECT treatments in a couple of weeks. But, I CAN tell you that I don't experience any side effects. I hope that helps even a wee bit.
> Nancy
Posted by shelley on January 9, 1999, at 11:01:36
In reply to Re: SSRI induced mania? and psychosis!, posted by Nancy on January 8, 1999, at 16:34:13
> > > > > I was on Zoloft in the past and now on Celexa for the past 6 weeks. With the Celexa, I have noticed what seems to be hypomanic states. This also happened with the Zoloft. Is this weird or does it occasionally happen? I would appreciate any info. Thanks. ~Mel
> > > > Hi Mel!! This happened to me, too. Zoloft and Prozac were the easiest to tolerate. Effexor and Serzone were the worst. I don't know how common this is. I've never had a manic episode without the "help" of an SSRI. Thanks for bringing it up. I'm glad I'm not the only one and am glad to hear others experiences. Thanks for the buzz on Celaxa. I've been wary of trying it for this particular reason. Shell
> > > Hi. Me too guys. SSRIs have sent me into full-blown psychotic manias!!! Talk about trippy. whoa!
> > > I've ended up in restraints in psych wards for days at a time while on my SSRI flight! I'm a certifiable lunatic! Although, I do have moments of lucid clarity. Not very often but, I am blessed with them now and then.
> > Me, too. I was just shy about mentioning the psychosis part of it. I didn't want to scare anybody who hasn't been through it. I'll never forget!!! Glad to see you're hear not there, Nancy!
>
> Guess we're just the lucky few on the lunatic fringe. ha ha. Psychosis is cool for a little while. Everything is like Disney Land, you know what I mean? Everything appears, well, UNUSUAL. And being Bipolar the voices that I hear say funny things, yea, like jokes and stuff. They can be coming from my clock radio (that's turned off) or from underneath my bed. We just chit-chat and giggle. Sometimes I hear music or chiors. Beautiful stuff. Oh, I could go on there's a lot of nifty stuff that goes along with being Bipolar psychotic (either while depressed or manic)!
> Remember, WE'RE NEVER ALONE...hee hee. I thought you had the experience to appreciate that.
> From the lunatic fringe,
> Nancy
Hmmm. More thoughts. I don't actually remember the year and half I spent hypomanic, manic, psychotic as a result of SSRIs. My doc also had me taking as many as 24 Halcion at night, which has amnesiac effects. All I remeber about being psychotic is lying on the floor, holding onto the walls, and screaming into the phone at my doc. Spotty memories of feeling really good while hypomanic. A note from my insurance company telling me I am now a "high risk" driver as I hit three different thinngs, two cars and a mail box while manic/psychotic, with very vague recollections. I don't know what to say, but be very careful, and if Doc #1 won't address this issue talk to doc #2. At the time I was also recommended for ECT, Nance. But seem to have struck a balance the past few months and the subject has been put on the back burner, so to speak. Let us know how it goes. Shell
Posted by David K. on January 11, 1999, at 5:19:58
In reply to Re: SSRI induced mania? and psychosis!, posted by shelley on January 9, 1999, at 11:01:36
Hi everybody... I went from feeling like a slug on Effexor and having to go to sleep at 7 or 8:00 at night to taking Celexa and finally falling asleep at midnight and waking up at five with a brief period or two in between of waking up and puttering around a little.
I also noticed that I'm really "chatty" on the Celexa. I talk and talk and talk. My Dr. said she doesn't THINK I'm hypomanic (I think that's the word she used...) my diagnosis is and always has been Major Depression.
Do you think I should be concerned? Could my Depression be changing into something else, or could it just be the meds? Or could it just be that since I'm feeling okay lately I've just got more to say? (ie, I'm less inhibited.)
Posted by Laurie on January 14, 1999, at 18:16:30
In reply to Re: SSRI induced mania? and psychosis!, posted by David K. on January 11, 1999, at 5:19:58
> Hi everybody... I went from feeling like a slug on Effexor and having to go to sleep at 7 or 8:00 at night to taking Celexa and finally falling asleep at midnight and waking up at five with a brief period or two in between of waking up and puttering around a little.
> I also noticed that I'm really "chatty" on the Celexa. I talk and talk and talk. My Dr. said she doesn't THINK I'm hypomanic (I think that's the word she used...) my diagnosis is and always has been Major Depression.
> Do you think I should be concerned? Could my Depression be changing into something else, or could it just be the meds? Or could it just be that since I'm feeling okay lately I've just got more to say? (ie, I'm less inhibited.)Hi David,
I don't think being chatty is really much to be concerned about! Matter of fact, it's probably pretty good that you feel like having so much to say after being depressed. I, too, have been feeling even a little happier on the celexia instead of the effexor. Don't worry about it, and enjoy it!
Laurie
Posted by Sean on January 15, 1999, at 17:07:48
In reply to Re: SSRI induced mania? and psychosis!, posted by Laurie on January 14, 1999, at 18:16:30
> > Hi everybody... I went from feeling like a slug on Effexor and having to go to sleep at 7 or 8:00 at night to taking Celexa and finally falling asleep at midnight and waking up at five with a brief period or two in between of waking up and puttering around a little.
> > I also noticed that I'm really "chatty" on the Celexa. I talk and talk and talk. My Dr. said she doesn't THINK I'm hypomanic (I think that's the word she used...) my diagnosis is and always has been Major Depression.
> > Do you think I should be concerned? Could my Depression be changing into something else, or could it just be the meds? Or could it just be that since I'm feeling okay lately I've just got more to say? (ie, I'm less inhibited.)
> Hi David,
> I don't think being chatty is really much to be concerned about! Matter of fact, it's probably pretty good that you feel like having so much to say after being depressed. I, too, have been feeling even a little happier on the celexia instead of the effexor. Don't worry about it, and enjoy it!
> LaurieWell this is certainly a deep question! It gets
right to the heart of how different types of
depression are defined and what is probably going
on at a neurochemical level.I am not a doc, but I've been reading on this
very subject lately because of my own experiences.
Here's what I think:- if you have ever had hypomanic states without
using an antidepressant drug, then it is likely
that you fall into the bipolar spectrum somewhere.
This could be cyclothymia or BP2 and you should
NOT be taking un-opposed antidepressants.- if the hypomania is AD induced, but you've never
been hypomanic on your own, you probably have
a more recurrent form of unipolar depression
which has atypical features. In other words,
the depression you have more resembles the
depressed phase of a bipolar person, or perhaps
something like dysthymia. So even if you are not
BP, you could wind up with a more rapid-cycling
and hard to treat form of unipolar. Apparently
in Europe, they treat this form of depression
with lithium. Some docs in the States do too.In any case, the Rx is tricky. I've tried to take
SSRI's and all I can say is HYPOMANIA CENTRAL.
These drugs feel like speed to me, and also have
an annoying "shallowing" effect on my sense of
person. Then the effect burns out and you have to
up the dose, and then it all happens again.At the moment, I'm chilling my cortex out with
*nothing* just to see what happens. Probably I will
get depressed and then have some hypomania for a
few months, and then get depressed etc... and
eventually decide to go for help again. But poly
drug therapy is so gnarly on the old body. I am
kind of scared of the anticonvulsants, although I
also have smell hallucinations and siezure-like
states which would benefit from these drugs.What a mess!
Posted by Mark on January 31, 1999, at 6:12:29
In reply to Re: SSRI induced mania? and psychosis!, posted by Sean on January 15, 1999, at 17:07:48
I am
> kind of scared of the anticonvulsants, although I
> also have smell hallucinations and siezure-like
> states which would benefit from these drugs.
> What a mess!
I expect that a neuroleptic would be a better
choice than an anti-convulsant for hallucinations.
Something Risperdol.To everyone else:
Prozac is virtually a stimulant now for me. My
bipolar is rather mild, but I seem to have every
known variation on the theme. I take Zoloft with
Depakote with good results, a high partial
response. The main side effect has been weight
gain and sedation, with the sedation having gone
away after a while.Zoloft doesn't (yet) cause mania; let's hope it
is some time before it begins doing it.
Posted by Lori on November 27, 2000, at 16:49:10
In reply to Re: anyone tried...yes, posted by Tess on January 9, 1999, at 7:26:56
> I respond well to AD's but the side effects are ghastly. On Zoloft I became a slug, feeling like I was in a cloud or spacey much of the time, very tranquil. Because of the extreme muscle and joint pain I switched to Celexa and the cloud is lifted. In its place is what I would call hypomania. I can clean my entire house, shovel snow, reformat my hard drive, go for a 3 mile run, etc. all in one day. One extreme to the other, both places suck. Hoping for some balance someday.
>
> > ...a non-SSRI anti-depressant with non-psychotic results? Or is the SSRI with a mood stabalizer a better option? I have yet to try Welbutrin. What's everyone's take on that one? I hear one of the side effects is weight loss :) and another is increased sex drive :) (definitely a blessing to those of us who have been on these "anti-libido" meds) ~Mel
> > Although I'm on the SSRI, Celexa, I'm also on Wellbutrin. Unfortunately, I can't give you info as to wether I like it or not. Because, I'm a treatment resistive Bipolar who is going to get ECT treatments in a couple of weeks. But, I CAN tell you that I don't experience any side effects. I hope that helps even a wee bit.
> > NancyI am too drug treatment resistant. I just finished my last of 7 ect treatments. My diagnosis is severe depression so I have never experienced mania until now, caused by the ect's. It feels so much better than being depressed I'm not quite sure what is going on. I have also been on every drug mentioned here plus some. I am currently on Prozac, Wellbutrin, and Remeron... as well as, thyroid medication. Nancy - I am wondering how you have responded to the ect... any feedback?
Also, Mel, I havn't found anything that will up my libito so when you do let me know... L
Posted by KarenRB53 on December 9, 2004, at 19:34:27
In reply to Re: anyone tried...yes, posted by Lori on November 27, 2000, at 16:49:10
I think the Prozac I've been taking for about 6 yrs has caused hypomania. My question is, does the hypomania go away when you finally wean off the medication? Thanks, Karen
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