Posted by musky on October 11, 2006, at 0:28:17
In reply to Re: OFF Remeron » jules354, posted by SLS on October 9, 2006, at 23:32:57
> >My understanding is this:
Depressive moods as well as anxiety are very much part of the withdrawl cycle.
The body doesnt start making the receptors right away..
this would explain that at first you may feel not too bad, then after the drug is out of the system , then the body operates on low numbers of receptors for awhile.. where you get the latent depression is when the body realizes it needs to make these receptors again , but doesnt quite have all the machinery in place yet(since the drug suppressed this).
When the body finally makes the machinery, you get your weeks where you will feel better,but again it takes time for the machinery to be in place and stay in place.. hence the up and down moods.
mood stability will occur when the body is in balance and again many factors affect the receptors being able to function again..good diet, proper sleep, exercise all play an important role in restoring this balance. even hormones and stress levels will have a dramatic effect.
Sure there is depression /anxiety but again. its all about management in a good healthy way until the body gets back into balance on its own.
pretty much everytime Im having a down time, i can trace it back to a ThOUGHT , sleep habit, stress level, or life event/situation/attitude, or in my case these days just balancing out from the Remeron..
We all have ups and downs and just need to be aware of what is UP and what is really down.. If the down lasts more than 2 weeks they say it is depression.. but of course this is a natural state if it is indeed warranted(ie. death of a loved one, financial stress, health issues).
So what do we do about it?? we manage it safely and get at the ROOT, the triggers.. not the belief that we are slipping,, that creates more anxiety..
but again Im not going to debate the obvious..JUst ride out the storm,, it passes.. even if it takes months, just stay on track and dont loose focus..
Musky
Just curious, how did you arrive at the weeks calculations - are they based on the avg. time it takes for a med to kick in and then the half-life, which affects how long it should take to quit your system?
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> That stuff was just off the top of my head and was based loosely on the time it takes for receptors to turn over (2-3 weeks) and the fact that most antidepressants effectively clear the body within a week (5 half-lives). The only exception is Prozac, which takes as long as 5 weeks to clear the body. I was being pretty liberal with the lengths of time I allowed for depression to appear or disappear, so it might not make sense to make special adjustments for Prozac. These are barely-educated guesses, nothing more. An empirical study of such a thing would be possible, but would take many patients to accomplish.
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> Generalizations:
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> 1. All withdrawal depressions begin proximal to the discontinuation of medication.
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> 2. All depressions beginning latent to the discontinuation of medication are relapses or the development of new conditions.
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> 3. Depressions beginning proximal to the discontinuation of medication can be either withdrawal or relapse. However, a worsening course indicates relapse.
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>
> - Scott
poster:musky
thread:692598
URL: http://www.dr-bob.org/babble/wdrawl/20061010/msgs/693748.html