Posted by Babak on September 23, 2011, at 13:02:23
In reply to Re: Do SSRI's cause dopamine depletion, posted by metafunj on September 12, 2009, at 11:23:47
> Just thought I'd throw this in here. I posted it in the tread about dopamine depletion on SSRIs being a myth. I hope this helps to answer the initial question.
>
> http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T26-4FNW4KX-2&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1009313094&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=bf1894ef55db5d4f4c51a0e41f6c6514
>
> Abstract
>
> Serotonin and dopamine transporter (SERT, DAT) availabilities have prospectively been investigated using [123I]β-CIT and single photon emission computed tomography in subjects with obsessivecompulsive disorder under treatment with the selective serotonin reuptake inhibitor citalopram. SERT availability decreased by a mean 36.5%, whereas DAT availability increased by about 40%. The data point at a citalopram induced modulation of both serotonergic and dopaminergic activity and support the notion of functional interactions of monoaminergic systems in the human brain.
>
> Keywords: Serotonin and dopamine transporters; Single photon emission computed tomography; β-CIT; Serotonin reuptake inhibitor; Obsessivecompulsive disorderI think different SSRIs have different effects on dopamine availablity. Citolopram is very different to Paxil.
poster:Babak
thread:883495
URL: http://www.dr-bob.org/babble/neuro/20110604/msgs/997665.html