Trk-b sigma-1r

Posted by linkadge on August 29, 2010, at 21:01:59 [reposted on August 30, 2010, at 0:49:14 | original URL]

Agents which act as both trk-b agonistand sigma-1r agonists would exhibit potent neurotrophic activity.
Fluvoxamine is a sigma agonist but not a trk-b agonist. Amitriptyline is a potent trk-b agonist but has lesser effect on sigma receptors.
what about combining fluvoxamine and amitriptyline? This would theoretically be potently neurotrophic.
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Trk-b sigma-1r linkadge 8/30/10
Re: Trk-b sigma-1r » linkadge Phillipa 8/30/10
Re: Trk-b sigma-1r ed_uk2010 9/3/10
Re: Trk-b sigma-1r linkadge 9/3/10
Re: Trk-b sigma-1r » linkadge morgan miller 9/3/10
Re: Trk-b sigma-1r ed_uk2010 9/3/10
Re: Trk-b sigma-1r SLS 9/3/10
Re: Trk-b sigma-1r » SLS ed_uk2010 9/3/10
Re: Trk-b sigma-1r SLS 9/3/10
Re: Trk-b sigma-1r Brainbeard 9/3/10
Re: Trk-b sigma-1r Brainbeard 9/3/10
Re: Trk-b sigma-1r » Brainbeard Phillipa 9/3/10
Re: Trk-b sigma-1r » Brainbeard Brainbeard 9/3/10
Re: Trk-b sigma-1r Brainbeard 9/3/10
Re: Trk-b sigma-1r » Brainbeard ed_uk2010 9/3/10
Re: Trk-b sigma-1r Brainbeard 9/3/10
Re: Trk-b sigma-1r linkadge 9/3/10
Re: Trk-b sigma-1r linkadge 9/3/10
Re: Trk-b sigma-1r linkadge 9/3/10
Re: Trk-b sigma-1r » linkadge Phillipa 9/3/10
Re: Trk-b sigma-1r » Brainbeard Phillipa 9/3/10
Re: Trk-b sigma-1r morgan miller 9/3/10
Re: Trk-b sigma-1r » morgan miller ed_uk2010 9/3/10
Re: Trk-b sigma-1r » linkadge ed_uk2010 9/3/10
Re: Trk-b sigma-1r » ed_uk2010 linkadge 9/3/10
Re: Trk-b sigma-1r linkadge 9/3/10
Re: Trk-b sigma-1r » linkadge ed_uk2010 9/3/10
Re: Trk-b sigma-1r violette 9/23/10

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