Psycho-Babble Neurotransmitters | advanced medication issues | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Re PEA/selegiline

Posted by undopaminergic on August 10, 2008, at 21:59:18

In reply to Re PEA/selegiline » undopaminergic, posted by christophrejmc on July 16, 2008, at 7:44:43

I used a solution of PEA and regulated the intake according to effect - perhaps a mouth full or two every 10-20 minutes. The precise consumption was never determined, but it also varied. In the beginning, there were distinct cardiovascular effects even of small amounts - the heart rate would drop from 75-70 bpm to under 60 due to the baroreflex triggered by the increase in pressure - probably up to 160 systolic and higher. Chronic consumption blunted the hypertensive effect to the point where blood pressure was normal while taking PEA and on the low side in its absence. (I wasn't taking memantine.)

It's interesting that you've found PEA more potent than the other sympathomimetics. It should be less potent from a cardiovascular point of view than at least tyramine. amphetamine and ephedrine, but more potent than methylphenidate amd cocaine.

> How often were/are you taking PEA, and how much?
>
> I've been using this combo off and on for about four years but I haven't been able to find a dose that's both effective and safe. I've combined a lot of proscribed sympathomimetics with MAOIs, but only PEA has caused severe hypertensive events.
>
> > Yes, precisely. I speculate that PEA+deprenyl+memantine might hold some promise for more sustained effect, based on the observations made by others concerning prevention of amphetamine-tolerance by memantine.
> >
>


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Neurotransmitters | Framed

poster:undopaminergic thread:834804
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/845458.html