Posted by JohnnyBLinux on July 16, 2008, at 0:56:14
In reply to Re: anyone have experience with pindolol augmentat » JohnnyBLinux, posted by Crotale on July 15, 2008, at 13:17:27
I take pindolol for high blood pressure. I would say that the combination of Lexapro + pindolol has not resulted in an enhancement of Lexapro. Again, it's hard to say because I didn't start with Lexapro.
As far as pindolol + an MAOI, here's what I found using the drug interaction checker at http://www.drugs.com/ :
pindolol and Nardil (phenelzine) (Minor Drug-Drug)
Monoamine oxidase inhibitors (MAOIs) may theoretically potentiate the hypotensive effect of some medications. This effect may stem from a gradual MAOI-induced accumulation of false neurotransmitters in peripheral adrenergic neurons that have minimal activity at alpha- and beta-adrenergic receptors, resulting in a functional block of sympathetic neurotransmission. Indeed, MAOIs alone quite commonly produce orthostatic hypotension. In addition, bradycardia has been reported with the concomitant use of beta blockers and MAOIs. The clinical significance of these effects is unknown. If these drugs are coadministered, patients should be monitored for evidence of an interaction (e.g., hypotension, orthostasis, bradycardia, tachycardia, dizziness, or syncope).I selected Nardil at random. It seems we have a number of Babblers on this medication. Hope this helps!
poster:JohnnyBLinux
thread:838118
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/839948.html