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Additional published papers on NAC, Depression,etc NKP

Posted by Mtom on January 19, 2021, at 12:46:55

In reply to Re: N-Acetyl Cysteine Newer Research, anyone try? Mtom, posted by NKP on January 18, 2021, at 16:08:25

Yes NKP I had read that article you linked. One has to be aware not only that there is often a trade-off in treating any condition, but that in many incidences, we don't know what the long-term trade-off might be. This goes for pharmaceutical drugs as well as supplements.

Caveats (and they may be significant) aside, I found another published paper, a 2016 meta-analysis of 5 Placebo controlled Clinical Trials examining N-acetyl Cysteine for depression. They found that NAC had a moderate effect over placebo in decreasing depressive symptoms and improving functionality over 12 to 24 week follow ups.
Link to download the PDF article: https://www.researchgate.net/publication/301816290_N-Acetylcysteine_in_Depressive_Symptoms_and_Functionality_A_Systematic_Review_and_Meta-Analysis/link/59e6ff84aca2721fc2304856/download

Here is another 2018 article "Application of N-Acetylcysteine in Psychiatric Disorders". It includes the abstract, not the full paper, but does have links to a number of tables from the paper summarizing results of studies investigating NAC for a number of psychiatric disorders. https://link.springer.com/chapter/10.1007%2F978-981-10-5311-5_12

> I presume that you are referring to the following thread of mine:
>
> http://www.dr-bob.org/babble/alter/20190907/msgs/1109502.html
>
> I've experienced near miraculous effects from NAC.
>
> I've also come across the following article however that argues that antioxidant supplementation is not necessarily a good thing:
>
> https://blogs.sciencemag.org/pipeline/archives/2019/10/04/n-acetyl-cysteine-a-warning-shot
>
> There is conflicting evidence that some cancers may be more common in people who supplement with antioxidants.


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