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Re: N-Acetyl Cysteine Newer Research, anyone try? Mtom

Posted by NKP on January 18, 2021, at 16:08:25

In reply to N-Acetyl Cysteine Newer Research, anyone try?, posted by Mtom on December 31, 2020, at 10:56:45

> Im reading papers suggesting that in depression, dysfunction of glutamatergic neurotransmission in the brain my be implicated. There is research suggesting that N-Acetyl Cysteine (NAC) regulates brain glutamate. Most articles say it is safe in low doses however other articles have cautions about using NAC for various reasons. Im still trying to read up on it.
>
> I see only one recent thread on NAC, with limited discussion. Research seems to have grown in recent years if you do a PubMed search for depression, bipolar disorder, schizophrenia, OCD, neuro-degenerative illnesses, etc.
>
> Studies seem to indicate it takes several months of supplementation to see an effect. Heres a link to download the PDF of a recent 2020 Review article (also discusses Vitamin D which I didnt read as I already supplement Vitamin D and have had my levels tested, are good). https://www.researchgate.net/publication/340469174_Vitamin_D_and_N-Acetyl_Cysteine_Supplementation_in_Treatment-Resistant_Depressive_Disorder_Patients_A_General_Review/link/5f69e02f92851c14bc8e098d/download
>
> Has anyone tried NAC recently, or researched it? What dose? Any side-effects or interactions with meds? Also what are the negatives of NAC supplementation (especially long term)?
>

I presume that you are referring to the following thread of mine:

http://www.dr-bob.org/babble/alter/20190907/msgs/1109502.html

I've experienced near miraculous effects from NAC.

I've also come across the following article however that argues that antioxidant supplementation is not necessarily a good thing:

https://blogs.sciencemag.org/pipeline/archives/2019/10/04/n-acetyl-cysteine-a-warning-shot

There is conflicting evidence that some cancers may be more common in people who supplement with antioxidants.


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URL: http://www.dr-bob.org/babble/alter/20190907/msgs/1113426.html