Posted by bleauberry on December 14, 2010, at 17:23:24
In reply to NAC for OCD. Cellulose + Silicon Dioxide! :(, posted by mogger on December 8, 2010, at 15:30:57
There are a few labs, for example Thorne Research, that realize certain fillers and buffers can actually interfere with absorption and metabolism. Of them, magnesium stearate is guilty. In low dose Naltrexone, calcium citrate is a common filler but needs to be avoided because it slows down absorption...with LDN they need fast absorption for it to work properly.
I'm sure this topic ties in to why we see so much difference between brand and generics. When someone claims a filler is "neutral", I automatically am suspicious. I say prove it. They can't. Only patient reactions like yours tell the truth.
> Hello,
>
> About 5 months ago my psychiatrist recommended that I take NAC 2400mg for OCD/Depression. I was all over it and began taking it. My doctor told me to be patient as studies have shown that NAC can begin to work at 9 weeks and actually is most effective at the 6 month mark. Well he is correct. I have been patient with it and it has paid off. It is incredibly powerful for my constantly over working brain that does not shut off. It has acted like a dampener and I have now been able to take a job and I am able to make travel plans for the first time in my life.
>
> I actually was taking 3600mg and felt that I was feeling a bit too spacey (in a good way) so dropped down to 2400mg and found that I needed a bit more so I went to 3000mg a day. The interesting this is that I switched brands to get a 500mg capsule instead of the 600mg capsule so I could take 3000mg evenly (1000mgX3 daily). I was using Swanson brand, 600mg, which capsules were made of gelatin and magnesium stearate (vegetable). I switched to Jarrow Brand 500mg and after about two weeks I began to struggle a bit with depression and horrific dry mouth. I became suspicious as the only thing I had done different was to swich brands. Clearly this was the problem so I looked at the side of the bottle. Well Jarrow's formula has silicon dioxide, cellulose, gelatin and magnesium stearate in each capsule. I really didn't feel great and was beginning to struggle so I went back to the Swanson brand to see if my suspicions were true and they are. After about 5 days switching back to Swanson I feel complete relief and back to where I was. I had no idea that ingredients in a capsule could have such a profound effect on me. I am wondering if anyone else has had the same negative reaction to either of these ingredients? I found an interesting website discussing that some fillers are not so good for us. Any thoughts and experiences?
>
> Joseph
poster:bleauberry
thread:972938
URL: http://www.dr-bob.org/babble/alter/20101202/msgs/973570.html