Posted by TheTaoOfPhil on July 5, 2010, at 12:40:54
In reply to Re: pyroluria supps...my experience...it's WORKING, posted by Lao Tzu on July 4, 2010, at 9:46:29
Hi,
I learned about Pyroluria from the book Depression Free Naturally by Joan Mathews Larson. Based on my family history (alcoholism left and right, bi-polar II, OCD,etc.) and the description of the anxiety syndrome in this book, however, I highly suspect that I have Pyroluria. Unfortunately the Bio Center laboratory in KS cannot do tests for people who live in NY state because of the AMA's hegemonic, nanny-state control of medical care here. My solution has been to try the supplements and just see if I get better.
The problem is that the regime suggested by Larson is quite extensive, and although none of these supplements is individually expensive, the whole thing adds up. She suggests the folowing:
B6 (Pyridoxine) 250 mg or more 2x daily
Zinc Picolinate 25 mg 2x daily
Pyroxial 5 phosphate 50 mg 2x daily
Manganeses gluconate 20 mg daily
Niacinamide 500 mg 2x daily
Pantothenic acid 500 mg 2x dailyShe also suggests magnesium and Vitamin C, but I have already been taking these for years so they're a no brainer.
I've been taking this regime for over a month. I cannot report a dramatic improvement, but I think it might be helping my concentration and energy level a bit. So I want to continue. But I also want to reduce the number of things I'm taking because it's a lot of money.
I tried the manganese at 10 mg daily for several weeks and then stopped because it did not seem to make a difference, and this is the one thing here that can have adverse effects. I think I noticed a little bit of twitching in my face while taking it but of course with my anxiety it's very easy for me to believe that the side effects I read about are happening to me :-(
Niacinamide is used in some circles at high doses as a benzo diazepine substitute, but I also read that it increases histamine levels. Does this mean that it can actually make your allergies worse? I already have really bad allergies.
As I understand it, the core deficiency in Pyroluria is B6 and Zinc, so in theory the only thing here that is absolutely necessary should be the B6 Pyriodixine and Zinc Picolinate. Is this the case, or should I keep any of the other things on that list?
Many thanks for your help. Thank God there's someplace where people are discussing these things.
poster:TheTaoOfPhil
thread:498689
URL: http://www.dr-bob.org/babble/alter/20100703/msgs/953376.html