Posted by Larry Hoover on January 23, 2007, at 11:36:10
In reply to Re: Is DHA necessary? » Larry Hoover, posted by saturn on January 22, 2007, at 20:43:12
> Hey Lar. Thanks for all the input. I have a further question: Even if the EPA to DHA conversion is inefficient and DHA is fully conditional, is it still not possible (or perhaps even likely) that a high EPA/DHA ratio might be more favorable than a lower one?
>
> Thanks...Peace...SaturnSure, it's possible. EPA is up against arichidonic acid (AA), the omega-6 eicosanoid precursor. We're flooded with the latter, from vegetable oil sources, and animals fed thereon. It may well be that the best functional defense is high EPA intake. However, DHA effects are not as obvious, and it might be a mistake to adjust intake based on what seems to have an obvious effect.
For example, there is a significant inverse relationship between DHA levels and the risk of dementia: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17101822
Also, a newly discovered substance derived from DHA released from neural membranes, neuroprotectin D1, can only be formed if there is DHA in the membrane to begin with.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16151530Lar
poster:Larry Hoover
thread:723138
URL: http://www.dr-bob.org/babble/alter/20070114/msgs/725532.html