Posted by tealady on September 25, 2006, at 1:01:36
In reply to whats up with GABA ?, posted by linkadge on September 24, 2006, at 15:53:56
> Ok, so the claim is that gaba does not cross the blood brain barrier.
>
> Now, I am unusually resistant to placebo effect,
> but gaba seems to actually have some calming effect.
>
> Whats up with this?
>
>
> Linkadgeit must be if you feel it?.. maybe it just crosses a little , like vitB1 (I've been "into " it lately).. well it only gets trnapsorted across the gut in small amounts..by transporters.. BUT it also crosses via a concentration gradient..so with megadoses you can get more across...maybe same with gaba and blood/brain barrier..if you take a lot more than is usual..maybe its a concentration gradient thing?..although yeah, i knwo the blood/brain barrier is more impervious etc
One thing that you may find interesting is the VitB1, by injections, is the most effective thing for lowering my anxiety /panic I have come across.. i can now breathe deeply..at least while resting, feel like i'm getting enough Oxygen, AND I'm not panicing about evrything and everyone...which IS a huge relief..
I'm still a bit of a worry guts, but its more of a high normal level..I read something about B1 and Gaba too
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2819010&dopt=Abstracthttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2075726&dopt=Abstract (no idea what this means)
.. so i'm not sure if that's how it works.. it does incr serotonin and dopamine though..here's some I found..
http://tealady-health.blog.co.uk/?tag=b1%20headings
if you scroll down for serotonin (under myofascial pain) and dopamine (in CFS)and follow the linksAlso B1 is a strong antiD.. if I miss it , on the 2nd day I really feel the depression..as well as the fatigue. If I ever try to come off it it's going to be one hell of a withdrawal..what i'm hoping though is i get fixed up by it and then I shouldn't notice the withdrawal.. it's happened with another girl so I'm hopeful.
Jan
poster:tealady
thread:688741
URL: http://www.dr-bob.org/babble/alter/20060817/msgs/689000.html