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Re: SJW effective in severe depression

Posted by linkadge on February 22, 2005, at 19:52:23

In reply to SJW effective in severe depression, posted by Larry Hoover on February 22, 2005, at 16:32:01

I guess people are giving the alternatives another go since some of the pharmacudicals have been linked to strange behavior.

When SSRI's were linked to increased suicidal thinking, I was about to say: "no duh"

I have always believed that SSRI's make me more suicidal, yet am either addicted, or benefit in some way.

I have said it a thousand times. I think the world would be a happier place if we had some potent 5-ht1a agonists.

Sure, SSri's give you a little activity there, but the 5-ht2a,2c, 5-ht3, 5-ht1d, 5-ht7 agonism just trashes any positive effect they may exert.
And makes you feel lousier on many different levels.

SJW has some 5-ht1a agonism, but some of the other actions make me a little wonkey. Dispite some claims to the contrary, I really think it has significant anticholinergic activity, cause to me it is a dumb drug.


Oh well.


Linkadge


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poster:linkadge thread:461878
URL: http://www.dr-bob.org/babble/alter/20050131/msgs/461972.html