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Re: Tryptophan adverse effects? » morel1

Posted by Larry Hoover on December 30, 2003, at 10:05:48

In reply to Re: Tryptophan vs 5HTP Please Help!!, posted by morel1 on December 27, 2003, at 17:37:02

> Just a concern but i read that tryptophan can cause bladder cancer and/or run a risk of developing diabetes if it runs your family anyone heard of this

There were some clues that linked tryptophan metabolic products (via the kynurenine pathway) to bladder cancer recurrence (not causing cancer, promoting recurrence), but that was later found to be due to genetic inability to process vitamin B6 (pyridoxine), or to deficiency in B6. I see no evidence that tryptophan is a risk factor for bladder cancer.

The relationship between tryptophan (serotonin) metabolism and diabetes is inverted to what you suggest. Diabetes disrupts serotonin synthesis, rather than tryptophan inducing diabetes.

Lar

 

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poster:Larry Hoover thread:256950
URL: http://www.dr-bob.org/babble/alter/20031218/msgs/294642.html