Posted by Larry Hoover on November 15, 2003, at 7:21:26
In reply to Re: Another question » Larry Hoover, posted by JLx on November 12, 2003, at 16:11:13
> > The dose of TMG that is effective varies substantially in different people. I can't tolerate more than a couple grams, tops. And I can't take it every day. I take 500-1000 mg, occasionally. But I know people who take eight or ten grams, every day.
>
> Ok, I know I have to experiment with how it feels but wrt homocysteine, what if there is an imbalance between the homocysteine-increasing effect of methionine and the homocysteine-lowering effect of TMG? Iow, do I have to make sure to take "x" amount of TMG if I take "xx" amount of methionine?If you're otherwise "normal", you will not develop hyperhomocysteinemia (high blood homocysteine) because the B12-dependent pathway back to methionine dominates. I would just monitor the psych effect of TMG, and not worry about homocysteine.
> (Forgive me if that's something you've already addressed -- I'm just not "getting" this in terms of the chemistry here.)
I think you're "getting" it quite well.
> Re previous post, just to be clear on this too, choline is NOT contraindicated for the undermethylated....despite what Dr. Walsh says?
>
> Thanks,
>
> JLUndermethylation goes along with oxidative stress, in my opinion, so I would support choline supps, but, I would recommend that soya lecithin is the source, rather than choline per se. Every time a supp is tried, it should be seen as an experiment to determine how *you* respond to the substance. I've seen far too many paradoxical responses (the opposite of what is expected) to say that there is a blanket answer, a simple rule to follow. That's where I have problems with Pfeiffer, Walsh, et al.
Lar
poster:Larry Hoover
thread:278139
URL: http://www.dr-bob.org/babble/alter/20031104/msgs/279965.html