Posted by undopaminergic on April 22, 2023, at 11:14:13
In reply to Re: To SLS » undopaminergic, posted by SLS on April 19, 2023, at 11:03:08
> Hi, UD.
Hi SLS.
>
> The following URL post was not addressed to you, but I hope it offers you reinforcement of my message. You and Rosalynn are probably the last people standing. I don't care. If people think I have no appreciation for what they have been through, the last four decades of MY life indicate otherwise. I was hoping to take some people along with me by having them reevaluate the behaviors that will ABSOLUTELY cause them to remain depressed, and might very well go to their graves without having lived without depression for decades. If people thought I returned just to criticize them, they would be right if I were judged by my more recent words. Nice didn't work.
>
> The best hope for those who are now gone lies in the novel treatments that will become available in the future. Some of them - maybe all of them - will be worth considering. I'm disappointed that zuranolone has taken so long to be approved by the FDA. However, it is scheduled to be so by late 2023. It is a member of a sequence of synthesized substances that acts as a positive positive allosteric modulator of GABA-A receptors. Believe it or not, the DEA has to sign off on zuranolone. I guess they want to make sure it doesn't have abuse potential like a benzodiazepine do have. Both drugs are positive modulators GABA-A receptors, albeit via different mechanism.
>
> Without prejudice, consider the source - again. I was not manic when I composed this second draft. It is a rather long narrative chronicling my adventures and what I learned from them.
>
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> http://www.dr-bob.org/babble/20220917/msgs/1121312.html
>
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> Take care of yourself. I think you have the best judgment among those who had been posting here regularly. Please use it.
>
>
> - ScottI'm in an awkward situation. I'm at a "tertiary" care psychiatric hospital, which one might assume would offer cutting-edge treatment. The problem is that they specialise in serious psychoses, meaning essentially schizophrenia and schizoaffective disorder. So they aren't focussing on my main complaints, of which is first and foremost depression, and secondarily, I'd probably rank ADHD.
Progress from treatment to treatment is excruciatingly slow. I was stuck at 5 mg vortioxetine for months, and I've now taken 10 mg for a little over a week. The (only?) good thing about all this is, from the perspective espoused by your referenced post, is that I get to (or am forced to) evaluate each treatment for enough time.
I did read it when you first posted it, but I don't feel it justified to re-read it now.
-undopaminergic
poster:undopaminergic
thread:1122008
URL: http://www.dr-bob.org/babble/20230117/msgs/1122044.html