Posted by undopaminergic on January 20, 2023, at 11:05:28
In reply to Re: Is there any evidence that Trazodone curbs OCD? » Lamdage22, posted by Jay2112 on January 19, 2023, at 21:27:59
> > Can anyone interpret the evidence? From what I can tell, it doesnt help much.
>
> No, not really. It was the 'med from hell' for me, BUT, I LOVED it's sister drug, nefadozone!! The most UNHARSH antidepressant. Marketed as Serzone in N.America. Don't know about it's effect on OCD, but it has calming effects via 5ht2a blockade.
>
> Jay
>
>It seems it is actually an *agonist* at the serotonin 5-HT2C receptor:
https://pubmed.ncbi.nlm.nih.gov/9618398/That would translate to an antidopaminergic effect.
-undopaminergic
poster:undopaminergic
thread:1121599
URL: http://www.dr-bob.org/babble/20230117/msgs/1121605.html