Posted by SLS on December 17, 2022, at 15:40:49
In reply to Re: Finally trying vortioxetine -- initial impressions, posted by NKP on December 17, 2022, at 6:54:48
> > > Hi UD:
> > >
> > > I too take vortioxetine, and find the nausea is very least when I take it later in the day/evening, with food. Ginger also helps. I have read the nausea may be from the cholinergic effects, which are a positive aspect of this drug. Ginger is an excellent anti-nauseant.
> > >
> >
> > Hi, Jay.
> >
> > Is that PRO-cholinergic? How does that work?
> >
> > Thanks.
> >
> >
> > - Scott
> >
> >
>
> Are there other antidepressants that are pro-cholinergic too? Might this account for the side-effect of excessive sweating that many antidepressants have?That's a great question. I never looked into it. The first antidepressant I ever tried
No. It is anticholinergic drugs (muscarinic receptor antagonists) that produce increased sweating.
- Pro-cholinergic drugs are depressogengic (pilocarpine).- Anti-cholinergic drugs are antidepressant (scopolamine).
Scopolamine has been studied as a rapid-acting antidepressant. I don't see much about it anymore. However. I haven't been following it.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1121240
URL: http://www.dr-bob.org/babble/20220917/msgs/1121268.html