Posted by SLS on August 22, 2022, at 18:00:03
In reply to Re: Would it be wise not to take GABAergics for sleep?, posted by Christ_empowered on August 22, 2022, at 17:03:17
> an occasional ativan for agitation or restoril for sleep is not ideal, but...effective, usually. and yet...
>
> longer term use creates problems for a lot of people. so, there's that. :-(
>
> never did well with z-hypnotics, personally. extra ativan or klonopin, yes. restoril, yes. but not so much ambien or sonata.
Unlike benzodiazepines, which bind to all GABA-A receptors, the Z- drugs are very selective for the α1-GABA-A receptor subtype. This receptor is most responsible for the hypnotic (sleep-inducing) properties of both the non-selective benzodiazepines and the selective Z- drugs. I took zolpidem (Ambien) for over a year. I was able to stop taking it abruptly without suffering the withdrawal syndrome associated with benzodiazepine discontinuation. The only discontinuation phenomenon I experienced was insomnia, but not total insomnia. I was able to sleep, but my sleep was very broken and light for a few days.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1120432
URL: http://www.dr-bob.org/babble/20220530/msgs/1120434.html