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Re: Reuptake Inhibition causes major probs for me

Posted by undopaminergic on February 22, 2022, at 8:21:32

In reply to Reuptake Inhibition causes major probs for me, posted by Jay2112 on February 21, 2022, at 13:49:14

>
> The RI's basically *force* the monoamine to hold in the pre-synaptic neuron.
>

They just keep the transporter protein from absorbing the neurotransmitter back into the presynaptic neuron.

> I question how healthy this mechanism is..it just seems so aggressive,

In fact it is a very passive process. So maybe you mean passive-aggressive, haha.

> compared to just making more monoamine available.

Well, possibly if you mean precursors like L-dopa or 5-HTP. But MAOIs would seem approximately equally "aggressive". On the other hand, however, to *force* the neurotransmitters out of their storage vesicles, like amphetamines do, that seems a lot more "aggressive" to me.

-undopaminergic


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URL: http://www.dr-bob.org/babble/20220128/msgs/1118718.html