Posted by undopaminergic on February 4, 2022, at 8:27:26
In reply to I can't believe I never thought of this combo., posted by SLS on February 3, 2022, at 9:48:46
> Hi, All.
>
> I can't believe my lack of imagination that this idea never occurred to me and that this article escaped me for 22 years.
>Well, it's not exactly an intuitive combination. Clomipramine (and imipramine to a lesser extent) already inhibits both serotonin and noradrenaline (norepinephrine) reuptake, which is the same thing that venlafaxine (supposedly) does, so wherein lies the mechanism of action behind the success of this combination?
-undopaminergic
poster:undopaminergic
thread:1118460
URL: http://www.dr-bob.org/babble/20220128/msgs/1118464.html