Posted by SLS on September 17, 2021, at 15:27:06
In reply to Re: Help..severe anger...., posted by undopaminergic on September 17, 2021, at 12:10:28
> > But: PEA administered during MAO-B inhibition in sufficient quantities yields a powerful antidepressant (or stimulant) effect.
> >
>
> Alternative theory: there could be a MAO-B substrate that is depressogenic. It may be hitherto unidentified as a MAO-B target.
>
> MPTP is a neurotoxin that produces Parkinson's disease. It is actually a precursor to the actual toxin; MAO-B converts MPTP to the MPP+ ion. There could be some other toxin that produces depression rather than Parkinson's, and which is *inactivated* by MAO-B, so that if you inhibit MAO-B, this substance is let loose on the CNS.This is an excellent thought. However, I'll need a few more years to understand it.
:-)- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1116908
URL: http://www.dr-bob.org/babble/20210723/msgs/1116988.html