Histamine H2-receptor antagonism

Posted by undopaminergic on November 19, 2020, at 4:24:14

Hi all,
I was wondering if anyone has any thoughts on or experience with histamine H2-receptor antagonism.
Famotidine has shown promising results in the treatment of negative symptoms in schizophrenia. Negative symptoms are very much like depression, including apathy and anhedonia.
Trimipramine is a potent and high-affinity histamine H2-antagonist. Clozapine is an inverse agonist at the receptor.
In schizohprenia (famotidine):
https://pubmed.ncbi.nlm.nih.gov/23764683/
In depression (ranitidine):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2417877/
-undopaminergic

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Histamine H2-receptor antagonism undopaminergic 11/19/20
Re: Histamine H2-receptor antagonism rjlockhart37 11/20/20
Re: Histamine H2-receptor antagonism » undopaminergic linkadge 11/22/20

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