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Re: Akathisia, meds , Pseudo-Parkinson and help pls.:(

Posted by undopaminergic on October 18, 2020, at 3:25:25

In reply to Re: Akathisia, meds , Pseudo-Parkinson and help pls.:( linkadge, posted by jay2112 on October 17, 2020, at 17:21:47

>
> And, I tried CBD, a few times, and it was just like a placebo. Surprisingly, cannabis is hit and miss, but I don't want to chance psychosis. One med that works *really* well is Lyrica..even way better than benzo's for for anxiety, and help's with depression too. But, I developed tolerance, and maxed it right out. Same with gabapentin.
>

I suggest you try a few opioids. First, you just make an experiment, to see if it helps at all. Then, if the experiment was successful, you take it on an occasional basis, suitably when the anxiety is particularly bad. Then, if necessary, you can take it on a more regular basis, but you need to be careful about the tolerance. Because the clinically available opioids are subtly (and sometimes notably) different, it is important to try several different ones. As I mentioned, they differ, and therefore, cross-tolerance is incomplete; this means you may be able to use opioid rotation in order to deal with the tolerance. Another option to keep doses low, is to add memantine, since this has proven to (in many cases) lower or inhibit opioid tolerance. Memantine may also be useful in its own right.

> It seems like clozapine does a lot of this, and about the agranulocytosis risk, it being only about 1 percent, and in some European countries, is only test for monthly, after being on the med for awhile.
>

I'm on clozapine. I thought it was worth trying, but I found it quite useless, and I want to quit but the doctors insist on continuing it. It disrupts the swallowing reflex, so there will be saliva on your pillow when you wake up in the morning. For the same reason, food gets stuck in your throat. Many people experience weight gain on clozapine, but I have escaped this problem.

-undopaminergic


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URL: http://www.dr-bob.org/babble/20200711/msgs/1112303.html