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Re: Dopa-responsive Dystonia - Meds

Posted by linkadge on July 25, 2020, at 17:52:31

In reply to Re: Dopa-responsive Dystonia - Meds linkadge, posted by pixel8mbb on July 25, 2020, at 15:45:58

Thank for describing more of your symptoms. It's very interesting that you have uncovered a mechanism for this.

>Caution Using Venlafaxine and Other Serotonin->norepinephrine Reuptake Inhibitors in Patients with >Dopa-Responsive Dystonia (Segawa Syndrome)

Yes. I read this study. I wasn't sure of the mechanism. Venlafaxine is fairly weak acting on norepinephrine. However, perhaps in combination with dopa, levels of norepinephrine become too elevated (dopa can increase norepinephrine as well).





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