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Re: COMT gene

Posted by undopaminergic on June 23, 2020, at 9:17:29

In reply to COMT gene, posted by alchemy on June 22, 2020, at 20:31:23

> I have some indicators that my COMT gene codes for slower COMT enzyme activity than most (along with 25% of the population). Research to date says that this translates into higher dopamine and norepinephrine.
>
> I always thought I needed more of them because I have no motivation or interests. So complicated!
>

Not everything makes sense. Schizophrenics are often thought to have excess dopamine, because dopamine antagonists ameliorate psychosis. Yet they have symptoms of a *lack* of dopamine, in the form of the so-called negative symptoms, which include anhedonia and apathy.

-undopaminergic


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poster:undopaminergic thread:1110974
URL: http://www.dr-bob.org/babble/20200511/msgs/1110980.html