Posted by undopaminergic on June 21, 2020, at 9:16:16
In reply to Re: My experience with Nardil, posted by Lamdage22 on June 21, 2020, at 0:12:22
> Yeah, believe me, I am embarassed by my delusions, too. Did the meds help you think more clearly?
>Not as far as I could tell. In fact, they (at least the quetiapine) dulled me through their anti-histamine effects.
> Or did you get over it without meds? For me, discontinuing Nardil helped a lot. The antipsychotics even more.
>For me, the passage of time, perhaps through using the time for contemplation and reasoning, seems to resolve delusions, slowly. I think (some) anti-psychotics can help speed up the process, through stimulating objective thinking, which may in turn promote certain aspects of critical thinking. When I say "some", I mean clozapine and especially trimipramine; incidentally, I've read they have similar receptor binding profiles. Note that this is just my experience, as it looks from my perspective; it may well be clozapine that does the main part and the addition of trimipramine amounts to reaching a "critical mass" of antipsychotic action.
Trimipramine is otherwise less effective as an antipsychotic than perazine according to a German study. See:
https://pubmed.ncbi.nlm.nih.gov/12734763/
(Full article available through https://sci-hub.se/ )-undopaminergic
poster:undopaminergic
thread:1110775
URL: http://www.dr-bob.org/babble/20200511/msgs/1110907.html