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Re: Nardil plus lorazepam SLS

Posted by undopaminergic on June 17, 2020, at 12:29:17

In reply to Re: Nardil plus lorazepam Jadde, posted by SLS on June 17, 2020, at 8:12:30

> I would consider taking both zolpidem (short half-life for sleep initiation) and lorazepam (longer half-life for sleep maintenance) at bedtime. It is perfectly safe with Nardil (I do it).
> The most effective treatment that I know of for sleep is a combination of triazolam (Halcion) for sleep initiation and lorazepam (Ativan) for sleep maintenance. You could take temazepam (Restoril) instead of lorazepam if you find it more helpful. I doubt you will find a doctor willing to prescribe triazolam, though.
> Another option would be to take quetiapine (Seroquel).

I would be concerned about sleep quality with benzodiazepines. I forgot the details, but I think most benzos inhibit REM-sleep. In my personal experience, sleep on midazolam (Dormicum; a short-acting benzo like triazolam) was worthless. Z-drugs (eg. zolpidem) have less adverse effects on REM.

As for anti-histamines (like quetiapine), other options are cyproheptadine (Periactin), doxepin, and trimipramine (Surmontil); they last of them has been reported to increase REM-sleep.

> Good luck.

Much needed in psychopharmacology!





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