Clomipramin, Tryptophan and Lithium in Combination

Posted by Skeletor on June 6, 2020, at 19:59:34

"Clomipramine, Tryptophan and Lithium in Combination for Resistant Endogenous Depression: Seven Case Studies" - August 1987 | A. S. Hale (a1), A. W. Procter (a2) and P. K. Bridges (a3)
https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/clomipramine-tryptophan-and-lithium-in-combination-for-resistant-endogenous-depression-seven-case-studies/F3A1B19433959744DCF32C36C7B4A28F#
https://www.reddit.com/r/depressionregimens/comments/e70kwi/clomipramine_tryptophan_and_lithium_in/?ref=share&ref_source=embed&utm_content=title&utm_medium=post_embed&utm_name=bf891a792752497cbec4bac2c877196f&utm_source=embedly&utm_term=e70kwi
Unquestionably an extreme combination, but it seems to exhibit powerful antidepressant effects. Clomipramine on its own is regarded by many as maybe the most powerful non-MAOI antidepressant, at least in clinical practice and inpatient care, although the side effects can be quite rough, but combined with Tryptophan and Lithium it seems to be further boosted in its effect size and response rate.
Maybe worth trying before hopping on ECT / MAOIs...
One has to be careful because it is a small sample case "study", but nonetheless quite interesting to read. I encourage all those who have a view or experience to share it with us, regarding the aforementioned medications and especially the combination. Greetings!

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Clomipramin, Tryptophan and Lithium in Combination Skeletor 6/6/20
Re: Clomipramin, Tryptophan and Lithium in Combination linkadge 6/7/20
Re: Clomipramin, Tryptophan and Lithium in Combination undopaminergic 6/7/20
Re: Clomipramin, Tryptophan and Lithium in Combination » linkadge Skeletor 6/7/20
Re: Clomipramin, Tryptophan and Lithium in Combination » undopaminergic Skeletor 6/7/20
Re: Clomipramin, Tryptophan and Lithium in Combination undopaminergic 6/7/20

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