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Re: Super probiotics of the near future for depression

Posted by Hugh on June 3, 2020, at 13:30:20

In reply to Super probiotics of the near future for depression, posted by Hugh on May 25, 2020, at 13:11:57

It's been widely reported how the mix of our gut bacteria can end up having a direct impact on our health. Now, new research points to a similar link between our wellbeing and the microbiome in the nose.

That's right - your nose is home to an entire host of microorganisms, just like the rest of your body. The different types of 'good' or 'bad' bacteria specific to the nasal cavities might end up protecting you from certain health issues, or putting you more at risk of others.

Lebeer and her team analysed nose bacteria from 100 healthy volunteers and 225 people with chronic rhinosinusitis, characterising 30 different families of bacteria in all. One family in particular stood out: lactobacilli.

These bacteria were more abundant in the healthy group of study participants up to 10 times more abundant in some cases. One particular strain of Lacticaseibacillus identified appeared to have adapted for nasal life, having evolved unique genes to manage the high oxygen levels in the cavity, and using thin tubes called fimbriae to help cling on.

In the end, the team created an experiment where one lactobacillus strain was sprayed into the noses of 20 healthy volunteers, twice daily for two weeks. While the nasal cavity typically filters out foreign bodies, here the bacteria were able to colonise.

That said, the study shows enough evidence that the microbiomes in our noses could affect our health, just like the microbiomes in our stomachs and elsewhere in the body.

Further down the line, we might be able to come up with safe, effective treatments that can grow certain nose bacteria for improved wellbeing.

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