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Re: 5 drugs better than ADs for bipolar disorder Hugh

Posted by SLS on May 5, 2020, at 8:54:55

In reply to 5 drugs better than ADs for bipolar disorder, posted by Hugh on May 4, 2020, at 15:19:42

Hi Hugh.

I hope all is well with you.

> Conclusion
> Findings from STEP-BD studies indicate that antidepressants should be avoided in most cases in treating acute depression in patients with bipolar disorder. Rather, one should choose from among five medications with a reasonable evidence-base for effectiveness and safety in treating or at least preventing bipolar depressions, namely: lithium, quetiapine, lamotrigine, lurasidone, and cariprazine -- or combinations of these.

I think lurasidone has garnered the most attention recently for bipolar depression. I wasn't too crazy about it. Cariprazine made me feel worse right from the beginning, and I stopped taking it immediately. I was not willing to take the chance that it might continue to make me feel worse. The half-life is extraordinarily long, and it might have meant weeks of hell. Lamotrigine helps me at a dosage of 300 mg/day. Not too long ago, I tried reducing it to 200 mg/day. I deteriorated quickly.

Aripirazole (Abilify) wasn't mentioned. I wonder why.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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