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Re: If you could choose from *everything* linkadge

Posted by undopaminergic on December 24, 2019, at 8:02:21

In reply to Re: If you could choose from *everything* undopaminergic, posted by linkadge on December 24, 2019, at 7:49:01

> I came off Ritalin for stupid reasons (I was taking 4 meds and could only afford 3). I chose to stay on lithium, Effexor and mirtazapine and drop Ritalin. I have relapsed in many ways coming off of it.
> I have lost confidence in my ability to get things done. This has filtered through to my job choices (turning down decent jobs that require a lot of paperwork / deskwork). In some ways this may not have been a bad idea (sitting for long periods of time on stimulants can't be great for the body). However, depression has returned as small tasks take me FOREVER to get done.
> The only time I can sit to watch a movie is when I am using pot. Although a bit impractical, certain doses of THC do actually improve my attention / hyperactivity.
> Linkadge

I wonder about the mirtazapine... it is an antagonist at alpha2-adrenoceptors. Meanwhile, guanfacine (Intuniv, Tenex) is an *agonist* at these receptors, improves working memory, and is used for ADHD. In other words, mirtazapine may be anti-cognitive, especially if you have ADHD.

I've read that vortioxetine (Brintellix, Trintellix) and lurasidone (Latuda) are pro-cognitive. In fact, I've read this about low-dose lithium as well.





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