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Re: If you could choose from *everything*

Posted by undopaminergic on December 23, 2019, at 0:41:31

In reply to Re: If you could choose from *everything* beckett2, posted by sigismund on December 22, 2019, at 23:14:00

> Haha
>
> Dilaudid.
>

Dilaudid (hydromorphone) is one of my choices too. I would be careful to attend to the issue of tolerance, finding a way a to prevent it, such as by taking it infrequently enough, or try combining with memantine or ketamine.

I would definitely try amineptine.

Perhaps the main thing I would try is selective dopamine reuptake inhibitors. Second most interesting option for me is tranylcypromine (Parnate). I might try high doses of rasagiline (I already tried it in low/regular doses).

I would try cocaine, but probably avoid smoking it.

I would experiment with other opioids than hydromorphone, including methadone, morphine, and oxymorphone. Perhaps try opioid rotation, to deal with tolerance.

Most modestly and realistically, I would try higher doses of trimipramine. As it is, this is the most realistic option.

Second most modestly, I would try vortioxetine (Brintellix, Trintellix).

I would try lithium, at least in lower doses.

I would try methamphetamine, but try to avoid chronic high doses, due to concerns about neurotoxicity.

I would try ketamine on its own.

I would try higher doses of scopolamine (already tried low doses -- Scopoderm). I would also try at least one other anticholinergic, orphenadrine.

I would probably try low doses of phencyclidine (PCP).

I would try some drugs I've already tried, including buprenorphine (Temgesic, Suboxone, Subutex). Also pramipexole (Sifrol, Mirapex). Maybe selegiline again too.

If necessary, I would try certain combinations, including some antipsychotics. Perhaps most promisingly, I would try (meth)amphetamine with tranylcypromine, if necessary to potentiate the latter.

-undopaminergic


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