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Re: Another q - would mixing 5mg of trintellix and TriedEveryMedication

Posted by undopaminergic on December 24, 2019, at 7:19:03

In reply to Another q - would mixing 5mg of trintellix and, posted by TriedEveryMedication on December 23, 2019, at 14:33:50

> Would mixing 5mg of Trintellix and 75mg of effexor be dangerous?

I'd say generally not. But it depends on how sensitive you are to serotonin reuptake inhibition.

> I know the two can lead to serotonin syndrome. But at a low dose?

No. The dose makes the poison. Also, serotonin toxicity from reuptake inhibitors is usually mild and not life-threatening. Still, it may be prudent to have some cyproheptadine (Periactin) available as an "antidote".





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