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Re: Can antidepressants work quickly?

Posted by SLS on July 15, 2019, at 18:20:08

In reply to Re: Can antidepressants work quickly?, posted by linkadge on July 15, 2019, at 17:28:18

> TCAs have a few mechanisms associated with more rapid antidepressant effect. For example, amitriptyline has anticholinergic properties as well as 5-ht2c antagonism. The antihistamine and calcium channel antagonism can help anxiety pretty quickly as well.
>
> A fast response can be a good sign.

Years ago on Psycho-Babble, people often reported feeling noticeably improved for a few days during the first week of antidepressant treatment. The response disappeared but reemerged 2-4 weeks later. That initial blip response seemed to be an indicator of eventual success. No guarantees, of course.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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URL: http://www.dr-bob.org/babble/20190513/msgs/1105286.html