Posted by linkadge on May 31, 2019, at 15:23:55
In reply to Re: Study:Amitriptyline most effective, experiences? » Lamdage22, posted by mtom on May 29, 2019, at 13:14:19
I could concur that amitriptyline is a very effective antidepressant. It was probably the only drug I have taken where I would say all core depressive symptoms vanished.
I would also say that the rate of anxiety is much lower than with SSRIS. By blocking certain serotonin receptors, histamine etc. it has a more calming effect (IMO) than SSRIs.
I would say that it is less sedating than mirtazpaine, and probably a stronger antidepressant. Although, it can have more side effects. The TCAs are considered 'dirtier' drugs in the sense that they have multiple targets. You may feel a bit more 'wonky' on amitriptyline than other drugs, but it does work for depression and anxiety for sure.
Linkadge
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thread:1104637
URL: http://www.dr-bob.org/babble/20190513/msgs/1104669.html